Mathematical modelling of spatio-temporal glioma evolution

M Papadogiorgaki, P Koliou, X Kotsiakis… - Theoretical Biology and …, 2013 - Springer
Background Gliomas are the most common types of brain cancer, well known for their
aggressive proliferation and the invasive behavior leading to a high mortality rate. Several …

Mathematical modelling of glioblastoma tumour development: a review

H Hatzikirou, A Deutsch, C Schaller… - … Models and Methods …, 2005 - World Scientific
During the past several years mathematical models have been applied to various aspects of
cancer dynamics, in particular avascular and vascular tumour growth, invasion …

Mathematically modeling the biological properties of gliomas: A review

NL Martirosyan, EM Rutter, WL Ramey… - Mathematical …, 2015 - aimsciences.org
Although mathematical modeling is a mainstay for industrial and many scientific studies,
such approaches have found little application in neurosurgery. However, the fusion of …

Mathematical modelling of a brain tumour initiation and early development: a coupled model of glioblastoma growth, pre-existing vessel co-option, angiogenesis and …

Y Cai, J Wu, Z Li, Q Long - PloS one, 2016 - journals.plos.org
We propose a coupled mathematical modelling system to investigate glioblastoma growth in
response to dynamic changes in chemical and haemodynamic microenvironments caused …

Hybrid mathematical model of glioma progression

ML Tanaka, W Debinski, IK Puri - Cell proliferation, 2009 - Wiley Online Library
Objectives: Gliomas are an important form of brain cancer, with high mortality rate.
Mathematical models are often used to understand and predict their behaviour. However …

Mathematical modeling of human glioma growth based on brain topological structures: study of two clinical cases

C Suarez, F Maglietti, M Colonna, K Breitburd… - PloS one, 2012 - journals.plos.org
Gliomas are the most common primary brain tumors and yet almost incurable due mainly to
their great invasion capability. This represents a challenge to present clinical oncology …

A multiscale model for glioma spread including cell-tissue interactions and proliferation

C Engwer, M Knappitsch… - … Biosciences & Engineering, 2015 - aimsciences.org
Glioma is a broad class of brain and spinal cord tumors arising from glia cells, which are the
main brain cells that can develop into neoplasms. They are highly invasive and lead to …

A multiscale modeling approach to glioma invasion with therapy

A Hunt, C Surulescu - Vietnam Journal of Mathematics, 2017 - Springer
We consider the multiscale model for glioma growth introduced in (Math. Biosci. Eng. 71:
443–460, 2016) to accommodate tumor heterogeneity by relying on the go-or-grow …

[HTML][HTML] A simple agent-based hybrid model to simulate the biophysics of glioblastoma multiforme cells and the concomitant evolution of the oxygen field

L Saucedo-Mora, MÁ Sanz, FJ Montáns… - Computer Methods and …, 2024 - Elsevier
Background and objectives: Glioblastoma multiforme (GBM) is one of the most aggressive
cancers of the central nervous system. It is characterized by a high mitotic activity and an …

[HTML][HTML] Diffusive modelling of glioma evolution: a review

A Roniotis, K Marias, V Sakkalis, M Zervakis - Journal of Biomedical …, 2010 - scirp.org
Gliomas, the most aggressive form of brain cancer, are known for their widespread invasion
into the tissue near the tumor lesion. Exponential models, which have been widely used in …