One of the toxic side effects of methotrexate (MTX) is enteritis. Aucubin, an iridoid glycoside
derived from traditional medicinal herbs, has been proven to have anti‐inflammation, anti …

Autophagy and NLRP3 inflammasome were associated with the process of colitis. Drugs
targeting NLRP3 inflammasome and autophagy to treat colitis are absent, and they are …

Flavone derivatives have been shown to possess anti-inflammatory properties in various
inflammation model systems; however, their underlying molecular mechanisms remain …

Gastric ulcer (GU) is a worldwide gastrointestinal disorder associated with NSAID use.
Recently, amentoflavone proved to be a potent autophagy modulator, antioxidant, anti …

Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects,
including inhibiting production of pro-inflammatory cytokines in macrophages. Autophagy …

Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects,
including inhibiting production of pro-inflammatory cytokines in macrophages. Autophagy …

Ulcerative colitis (UC) is a recurrent chronic inflammatory disease. The symptom of UC is
mainly diarrhea including bloody stools. Increasing evidence has suggested that …

Introduction Cynaroside exhibits various biological properties, including anti-inflammatory,
antiviral, antitumor, and cardioprotective effects. However, its involvement in methotrexate …

Aims Aucubin, an iridoid glycoside, was isolated from seeds of Eucommia ulmoides Oliver.
This study was aimed to evaluate the protective effect of aucubin against ethanol-induced …

Background Genetic studies have strongly linked autophagy to Crohn's disease (CD), and
stimulating autophagy in CD patients may be therapeutically beneficial. The aim of this study …