BINDTI: a bi-directional intention network for drug-target interaction identification based on attention mechanisms

L Peng, X Liu, L Yang, L Liu, Z Bai… - IEEE Journal of …, 2024 - ieeexplore.ieee.org
The identification of drug-target interactions (DTIs) is an essential step in drug discovery. In
vitro experimental methods are expensive, laborious, and time-consuming. Deep learning …

IIFDTI: predicting drug–target interactions through interactive and independent features based on attention mechanism

Z Cheng, Q Zhao, Y Li, J Wang - Bioinformatics, 2022 - academic.oup.com
Motivation Identifying drug–target interactions is a crucial step for drug discovery and
design. Traditional biochemical experiments are credible to accurately validate drug–target …

MINDG: a drug–target interaction prediction method based on an integrated learning algorithm

H Yang, Y Chen, Y Zuo, Z Deng, X Pan, HB Shen… - …, 2024 - academic.oup.com
Motivation Drug–target interaction (DTI) prediction refers to the prediction of whether a given
drug molecule will bind to a specific target and thus exert a targeted therapeutic effect …

[HTML][HTML] MCL-DTI: using drug multimodal information and bi-directional cross-attention learning method for predicting drug–target interaction

Y Qian, X Li, J Wu, Q Zhang - BMC bioinformatics, 2023 - Springer
Background Prediction of drug–target interaction (DTI) is an essential step for drug discovery
and drug reposition. Traditional methods are mostly time-consuming and labor-intensive …

[HTML][HTML] Ammvf-dti: A novel model predicting drug–target interactions based on attention mechanism and multi-view fusion

L Wang, Y Zhou, Q Chen - International Journal of Molecular Sciences, 2023 - mdpi.com
Accurate identification of potential drug–target interactions (DTIs) is a crucial task in drug
development and repositioning. Despite the remarkable progress achieved in recent years …

An interpretable framework for drug-target interaction with gated cross attention

Y Kim, B Shin - Machine Learning for Healthcare …, 2021 - proceedings.mlr.press
In silico prediction of drug-target interactions (DTI) is significant for drug discovery be-cause
it can largely reduce timelines and costs in the drug development process. Specifically, deep …

[HTML][HTML] GSRF-DTI: a framework for drug-target interaction prediction based on a drug-target pair network and representation learning on a large graph

Y Zhu, C Ning, N Zhang, M Wang, Y Zhang - BMC biology, 2024 - Springer
Background Identification of potential drug-target interactions (DTIs) with high accuracy is a
key step in drug discovery and repositioning, especially concerning specific drug targets …

Drug-target interaction prediction using multi-head self-attention and graph attention network

Z Cheng, C Yan, FX Wu, J Wang - IEEE/ACM Transactions on …, 2021 - ieeexplore.ieee.org
Identifying drug-target interactions (DTIs) is an important step in the process of new drug
discovery and drug repositioning. Accurate predictions for DTIs can improve the efficiency in …

DTIGCCN: Prediction of drug-target interactions based on GCN and CNN

K Shao, Z Zhang, S He, X Bo - 2020 IEEE 32nd International …, 2020 - ieeexplore.ieee.org
Drug-target interaction (DTI) prediction plays an important role in drug repositioning, drug
discovery, and drug design. In recent years, some DTI prediction methods based on …

MCANet: shared-weight-based MultiheadCrossAttention network for drug–target interaction prediction

J Bian, X Zhang, X Zhang, D Xu… - Briefings in …, 2023 - academic.oup.com
Accurate and effective drug–target interaction (DTI) prediction can greatly shorten the drug
development lifecycle and reduce the cost of drug development. In the deep-learning-based …