Poly (disulfide) s: from synthesis to drug delivery

R Zhang, T Nie, Y Fang, H Huang, J Wu - Biomacromolecules, 2021 - ACS Publications
Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …

Pyridyl disulfide-based thiol–disulfide exchange reaction: Shaping the design of redox-responsive polymeric materials

I Altinbasak, M Arslan, R Sanyal, A Sanyal - Polymer Chemistry, 2020 - pubs.rsc.org
Recent years have witnessed an increase in the utilization of stimuli-responsive polymers in
various areas of materials and biological sciences. In particular, disulfide linkage containing …

Bioreducible polymers for therapeutic gene delivery

YS Lee, SW Kim - Journal of Controlled Release, 2014 - Elsevier
Most currently available cationic polymers have significant acute toxicity concerns such as
cellular toxicity, aggregation of erythrocytes, and entrapment in the lung capillary bed …

Construction of disulfide containing redox-responsive polymeric nanomedicine

S Fu, CM Rempson, V Puche, B Zhao, F Zhang - Methods, 2022 - Elsevier
Disulfide bonds (SS) are widely found in chemistry, biology, and materials science. Polymer
nanomaterials containing disulfide bonds with a variety of excellent properties have great …

Architecture-controlled ring-opening polymerization for dynamic covalent poly (disulfide) s

Y Liu, Y Jia, Q Wu, JS Moore - Journal of the American Chemical …, 2019 - ACS Publications
A strategy is reported for controlling the architecture of poly (disulfide) s by ring-opening
polymerization. Aryl thiol initiators shift the ring–chain equilibrium to yield cyclic polymers …

Single-molecule kinetics of growth and degradation of cell-penetrating poly (disulfide) s

GS Pulcu, NS Galenkamp, Y Qing… - Journal of the …, 2019 - ACS Publications
The delivery of therapeutic agents into target cells is a challenging task. Cell penetration and
intracellular targeting were recently addressed with biodegradable cell-penetrating poly …

Poly (disulfide) s

EK Bang, M Lista, G Sforazzini, N Sakai, S Matile - Chemical Science, 2012 - pubs.rsc.org
Don't forget poly (disulfide) s. There is a rich literature pointing out the advantages of the
dynamic nature of single disulfide bridges to explore self-sorting, biomolecular engineering …

Substrate-initiated synthesis of cell-penetrating poly (disulfide) s

EK Bang, G Gasparini, G Molinard, A Roux… - Journal of the …, 2013 - ACS Publications
Lessons from surface-initiated polymerization are applied to grow cell-penetrating poly
(disulfide) s directly on substrates of free choice. Reductive depolymerization after cellular …

Intracellular delivery of functional proteins and native drugs by cell-penetrating poly (disulfide) s

J Fu, C Yu, L Li, SQ Yao - Journal of the American Chemical …, 2015 - ACS Publications
The efficient delivery of bioactive compounds into cells is a major challenge in drug
discovery. We report herein the development of novel methods for intracellular delivery of …

Controlled and Regioselective Ring-Opening Polymerization for Poly (disulfide) s by Anion-Binding Catalysis

T Du, B Shen, J Dai, M Zhang, X Chen… - Journal of the …, 2023 - ACS Publications
Poly (disulfide) s are an emerging class of sulfur-containing polymers with applications in
medicine, energy, and functional materials. However, the constituent dynamic covalent S–S …