Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD-based protein subunit vaccine (ZF2001) against COVID-19 in adults: two randomised …

S Yang, Y Li, L Dai, J Wang, P He, C Li… - The Lancet Infectious …, 2021 - thelancet.com
Background Although several COVID-19 vaccines have been developed so far, they will not
be sufficient to meet the global demand. Development of a wider range of vaccines, with …

Safety, tolerability, and immunogenicity of a SARS-CoV-2 recombinant spike RBD protein vaccine: A randomised, double-blind, placebo-controlled, phase 1-2 clinical …

F Hernández-Bernal, MC Ricardo-Cobas… - …, 2022 - thelancet.com
Background Multiple vaccine candidates against COVID-19 are currently being evaluated.
We evaluate the safety and immunogenicity protein of a novel SARS-CoV-2 virus receptor …

Efficacy and safety of the RBD-dimer–based COVID-19 vaccine ZF2001 in adults

L Dai, L Gao, L Tao, SR Hadinegoro… - New England journal …, 2022 - Mass Medical Soc
Background The ZF2001 vaccine, which contains a dimeric form of the receptor-binding
domain of severe acute respiratory syndrome coronavirus 2 and aluminum hydroxide as an …

A tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates

Y An, S Li, X Jin, J Han, K Xu, S Xu, Y Han… - Emerging microbes & …, 2022 - Taylor & Francis
Safe, efficacious, and deployable vaccines are urgently needed to control COVID-19 in the
large-scale vaccination campaigns. We report here the preclinical studies of an approved …

Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial

L Bravo, I Smolenov, HH Han, P Li, R Hosain… - The Lancet, 2022 - thelancet.com
Background A range of safe and effective vaccines against SARS CoV 2 are needed to
address the COVID 19 pandemic. We aimed to assess the safety and efficacy of the COVID …

[HTML][HTML] Evaluation of safety and immunogenicity of receptor-binding domain-based COVID-19 vaccine (Corbevax) to select the optimum formulation in open-label …

S Thuluva, V Paradkar, SR Gunneri, V Yerroju… - …, 2022 - thelancet.com
Background We assessed the efficacy of a receptor-binding domain (RBD)-based protein
subunit COVID-19 vaccine. Methods A randomised Phase-1/2 trial followed by a Phase-2 …

Safety and immunogenicity of a recombinant interferon-armed RBD dimer vaccine (V-01) for COVID-19 in healthy adults: a randomized, double-blind, placebo …

Y Liao, Y Li, R Pei, X Fang, P Zeng, R Fan… - Emerging microbes & …, 2021 - Taylor & Francis
Safe and effective vaccines are still urgently needed to cope with the ongoing COVID-19
pandemic. Recently, we developed a recombinant COVID-19 vaccine (V-01) containing …

Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial

S Xia, Y Zhang, Y Wang, H Wang, Y Yang… - The Lancet infectious …, 2021 - thelancet.com
Background The ongoing COVID-19 pandemic warrants accelerated efforts to test vaccine
candidates. We aimed to assess the safety and immunogenicity of an inactivated severe …

[HTML][HTML] Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase …

SL Xia, YT Zhang, YX Wang, H Wang… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background Although SARS-CoV-2 infection often causes milder symptoms in
children and adolescents, young people might still play a key part in SARS-CoV-2 …

A phase 3, randomised, double-blind, placebo-controlled clinical trial evaluation of the efficacy and safety of a SARS-CoV-2 recombinant spike RBD protein vaccine in …

F Hernández-Bernal, MC Ricardo-Cobas… - The Lancet Regional …, 2023 - thelancet.com
Background The pandemic of COVID-19 raised the urgent need for safe and efficacious
vaccines against SARS-CoV-2. We evaluated the efficacy and safety of a new SARS-CoV-2 …