Renal fibrosis is an unavoidable end result of all forms of progressive chronic kidney
diseases (CKD). Discovery of efficacious drugs against renal fibrosis is in crucial need. In a …

Aims Renal fibrosis is the most common final stage of progressive renal disease,
characterized by fibroblast proliferation, fibroblast-to-myofibroblast differentiation and …

Artemisinin has immunomodulatory, anti-inflammatory, and antifibrotic effects. Some studies
have demonstrated that artemisinins have a protective effect on the kidney. DHA is a …

Renal fibrosis is the hallmark of chronic kidney diseases (CKD) and its development and
progression are significantly affected by epigenetic modifications. Rhein, a plant-derived …

Chronic kidney disease is increasingly considered to be a worldwide public health problem
and usually leads to renal fibrosis. In the present study, curcumin, a polyphenol pigment …

Renal tubule-interstitial fibrosis is related to chronic kidney disease progression and a
typical feature of the aging kidney. Epigenetic modifications of fibrosis-prone genes regulate …

Aim The present study aims to investigate the protective effects of artemisinin (ATZ) on early
renal damage in experimental diabetic rats and its probable mechanism. Methods Models of …

Renal interstitial fibrosis is a common outcome of chronic renal diseases. Amygdalin is one
of a number of nitrilosides, the natural cyanide‑containing substances abundant in the seeds …

Aims Peroxisome proliferator-activated receptor-alpha (PPARα) levels are markedly lower in
the kidneys of chronic kidney disease (CKD) patients. Fibrates (PPARα agonists) are …

Artemisinin (Art) is isolated from Artemisia annua L. and known as the most effective
antimalaria drugs. Previous studies demonstrated that it could exert an immune‐regulatory …