Targeting Ferroptosis for Lung Diseases: Exploring Novel Strategies in Ferroptosis‐Associated Mechanisms

TL Ma, Y Zhou, C Wang, L Wang… - Oxidative medicine …, 2021 - Wiley Online Library
Ferroptosis is an iron‐dependent regulated necrosis characterized by the peroxidation
damage of lipid molecular containing unsaturated fatty acid long chain on the cell …

Recent progress of ferroptosis in lung diseases

S Yu, J Jia, J Zheng, Y Zhou, D Jia… - Frontiers in cell and …, 2021 - frontiersin.org
Ferroptosis is a new form of programmed cell death due to iron-dependent excess
accumulation of lipid peroxides and differs from other programmed cell deaths in …

Role of ferroptosis in lung diseases

W Xu, H Deng, S Hu, Y Zhang, L Zheng… - Journal of …, 2021 - Taylor & Francis
Ferroptosis is a new type of programmed cell death characterized by intracellular iron
accumulation and lipid peroxidation that leads to oxidative stress and cell death. The …

Induction mechanism of ferroptosis: a novel therapeutic target in lung disease

L Pan, C Gong, Y Sun, Y Jiang, X Duan… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is a newly discovered form of non-apoptotic regulatory cell death driven by iron-
dependent lipid peroxidation. Ferroptosis significantly differs from other forms of cell death in …

Multifaceted roles of ferroptosis in lung diseases

Y Li, Y Yang, Y Yang - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Ferroptosis is a distinct type of programmed cell death (PCD) that depends on iron and is
characterized by the accumulation of intracellular iron, exhaustion of glutathione …

Ferroptosis in pulmonary fibrosis: an emerging therapeutic target

C Wang, S Hua, L Song - Frontiers in Physiology, 2023 - frontiersin.org
In recent years, the role of ferroptosis in pulmonary fibrosis has garnered increasing interest
as a potential therapeutic target. Pulmonary fibrosis is a pathological process characterized …

Targeting ferroptosis as a vulnerability in pulmonary diseases

L Yang, L Cao, X Zhang, B Chu - Cell Death & Disease, 2022 - nature.com
Ferroptosis is an iron-dependent regulated cell death marked by excessive oxidative
phospholipids (PLs). The polyunsaturated fatty acids-containing phospholipids (PUFA-PLs) …

Molecular mechanisms of ferroptosis and its role in pulmonary disease

N Tao, K Li, J Liu - Oxidative Medicine and Cellular Longevity, 2020 - Wiley Online Library
Ferroptosis is a new mode of cell death that is characterized by the excessive accumulation
of iron and lipid peroxides. It has unique morphological changes and disparate biochemical …

Ferroptosis and its potential role in lung cancer: updated evidence from pathogenesis to therapy

K Chen, S Zhang, J Jiao, S Zhao - Journal of Inflammation …, 2021 - Taylor & Francis
Lung cancer is characterized by high morbidity and mortality rates, and its occurrence is
associated with many types of cell death. As a new form of regulated cell death, ferroptosis is …

The role of ferroptosis in lung cancer

S Wu, C Zhu, D Tang, QP Dou, J Shen, X Chen - Biomarker research, 2021 - Springer
Lung cancer is one of the most common cancers in the world. Although medical treatment
has made impressive progress in recent years, it is still one of the leading causes of cancer …