Microvirin (MVN) is one of the human immunodeficiency virus (HIV-1) entry inhibitor lectins,
which consists of two structural domains sharing 35% sequence identity and contrary to …

Lectins that bind surface envelope glycoprotein gp120 of HIV with high avidity can potently
inhibit viral entry. Yet properties such as multivalency that facilitate strong interactions can …

Type I interferon is known to inhibit HIV-1 replication through the induction of interferon
stimulated genes (ISG), including a number of HIV-1 restriction factors. To better understand …

Microvirin (MVN), a recently isolated lectin from the cyanobacterium Microcystis aeruginosa
PCC7806, shares 33% identity with the potent anti-human immunodeficiency virus (HIV) …

Background Induction of broad immune responses at mucosal site remains a primary goal
for most vaccines against mucosal pathogens. Abundance of evidence indicates that the co …

Abstract Cyanovirin-N (CV-N) is a mannose-binding lectin that inhibits HIV-1 infection by
blocking mannose-dependent target cell entry via C-type lectins. Like HIV-1, Mycobacterium …

Although it has been shown that some mannose-binding lectins (MBLs) exhibit significant
activity against HIV infection, little is known about whether N-acetylgalactosamine (GalNAc) …

Human immunodeficiency virus (HIV) is the primary etiologic agent responsible for the AIDS
pandemic. In this work, we used a chimeric recombinant protein strategy to test the …

ABSTRACT Serine incorporator 5 (Ser5), a transmembrane protein, has recently been
identified as a host antiviral factor against human immunodeficiency virus (HIV)-1 and …

Human mannose receptor 1 (hMRC1) is a transmembrane glycoprotein that belongs to the
C-type lectin family and is expressed on the surface of most tissue macrophages. hMRC1 …