Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis

MS Petrov, S Shanbhag, M Chakraborty, ARJ Phillips… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS: There is no consistency between the individual studies in the
literature on whether organ failure (OF) or infected pancreatic necrosis (IPN) is the main …

Infected pancreatic necrosis due to multidrug-resistant organisms and persistent organ failure predict mortality in acute pancreatitis

S Jain, SJ Mahapatra, S Gupta… - Clinical and translational …, 2018 - journals.lww.com
Background: Organ failure determines outcome in acute pancreatitis (AP). It is controversial
if infected pancreatic necrosis (IPN) is also an independent determinant of mortality. We …

Impact of characteristics of organ failure and infected necrosis on mortality in necrotising pancreatitis

NJ Schepers, OJ Bakker, MG Besselink, UA Ali… - Gut, 2019 - gut.bmj.com
Objective In patients with pancreatitis, early persisting organ failure is believed to be the
most important cause of mortality. This study investigates the relation between the timing …

Predictors of severe and critical acute pancreatitis: a systematic review

CJ Yang, J Chen, ARJ Phillips, JA Windsor… - Digestive and Liver …, 2014 - Elsevier
Background Persistent organ failure and infected pancreatic necrosis are major
determinants of mortality in acute pancreatitis, but there is a gap in the literature assessing …

Association of extent and infection of pancreatic necrosis with organ failure and death in acute necrotizing pancreatitis

PK Garg, K Madan, GK Pande, S Khanna… - Clinical …, 2005 - Elsevier
Background & Aims: Organ failure is the usual cause of death in acute necrotizing
pancreatitis. Our objective was to study whether the extent and infection of pancreatic …

The role of organ failure and infection in necrotizing pancreatitis: a prospective study

Q Guo, A Li, Q Xia, X Liu, B Tian, G Mai… - Annals of …, 2014 - journals.lww.com
Objective: To clarify the roles of organ failure and infection in the outcome of necrotizing
pancreatitis. Background: Results of previous cohort studies that focused on the roles of …

Infection increases mortality in necrotizing pancreatitis: a systematic review and meta-analysis

M Werge, S Novovic, PN Schmidt, LL Gluud - Pancreatology, 2016 - Elsevier
Objectives To assess the influence of infection on mortality in necrotizing pancreatitis.
Methods Eligible prospective and retrospective studies were identified through manual and …

Acute pancreatitis: bench to the bedside

SJ Pandol, AK Saluja, CW Imrie, PA Banks - Gastroenterology, 2007 - gastrojournal.org
Acute pancreatitis is an acute inflammatory process of the pancreas that frequently involves
peripancreatic tissues and at times remote organ systems. The severity of the disease varies …

Does mortality occur early or late in acute pancreatitis?

M Mutinga, A Rosenbluth, SM Tenner, RR Odze… - International journal of …, 2000 - Springer
Several prior studies have suggested that 80% of deaths in acute pancreatitis occur late as a
result of pan-creatic infection. Others have suggested that approx half of deaths occur early …

Determinants of severity in acute pancreatitis: a nation-wide multicenter prospective cohort study

H Sternby, F Bolado, HJ Canaval-Zuleta… - Annals of …, 2019 - journals.lww.com
Objective: The aim of this study was to compare and validate the different classifications of
severity in acute pancreatitis (AP) and to investigate which characteristics of the disease are …