Why does COVID‐19 kill more elderly men than women? Is there a role for testosterone?

V Papadopoulos, L Li, M Samplaski - Andrology, 2021 - Wiley Online Library
Background Recent epidemiological data indicate that there may be a gender predisposition
to COVID‐19, with men predisposed to being most severely affected, and older men …

Worse progression of COVID‐19 in men: is testosterone a key factor?

VA Giagulli, E Guastamacchia, T Magrone, E Jirillo… - …, 2021 - Wiley Online Library
Background The novel severe acute respiratory syndrome coronavirus (SARS‐CoV‐2)
disease 2019 (COVID‐19) seems to have a worse clinical course among infected men …

Testosterone's Role in COVID-19

JM Auerbach, M Khera - The Journal of Sexual Medicine, 2021 - academic.oup.com
ABSTRACT COVID-19 consistently displays a higher mortality in males. This sex-specific
difference in outcomes is seen not only in the current COVID-19 pandemic, but also in prior …

Testosterone in males with Covid‐19: a 12‐month cohort study

A Salonia, M Pontillo, P Capogrosso, E Pozzi… - …, 2023 - Wiley Online Library
Background Male patients with COVID‐19 have been found with reduced serum total
testosterone (tT) levels and with more severe clinical outcomes. Objectives To assess total …

Severely low testosterone in males with COVID‐19: a case‐control study

A Salonia, M Pontillo, P Capogrosso, S Gregori… - …, 2021 - Wiley Online Library
Background Circulating androgens could have a relevant pathobiological role in clinical
outcomes in men with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …

Testosterone deficiency is a risk factor for severe COVID-19

L Lanser, FR Burkert, L Thommes, A Egger… - Frontiers in …, 2021 - frontiersin.org
Background Male sex is related to increased COVID-19 severity and fatality although
confirmed infections are similarly distributed between men and women. The aim of this …

Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection

S Salciccia, F Del Giudice… - Therapeutic …, 2021 - journals.sagepub.com
The pandemic acute respiratory syndrome coronavirus 2 (SARS-CoV-2) named COVID-19
is causing a severe health emergency, and an individual's hormonal milieu may play an …

The relationship of serum testosterone levels with the clinical course and prognosis of COVID‐19 disease in male patients: a prospective study

AE Cinislioglu, N Cinislioglu, SO Demirdogen… - …, 2022 - Wiley Online Library
Background A potential role of testosterone among sex hormones has been hypothesized in
identifying sex‐related differences in the clinical consequences of severe acute respiratory …

Sex differences in COVID-19: the role of androgens in disease severity and progression

MS Mohamed, TC Moulin, HB Schiöth - Endocrine, 2021 - Springer
Abstract Purpose Throughout the SARS-CoV2 pandemic, multiple reports show higher
percentages of hospitalization, morbidity, and mortality among men than women, indicating …

Testosterone in males with COVID‐19: a 7‐month cohort study

A Salonia, M Pontillo, P Capogrosso, S Gregori… - …, 2022 - Wiley Online Library
Background Circulating testosterone levels have been found to be reduced in men with
severe acute respiratory syndrome coronavirus 2 infection, COVID‐19, with lower levels …