Dynamical modelling of viral infection and cooperative immune protection in COVID-19 patients

Z Zhou, D Li, Z Zhao, S Shi, J Wu, J Li… - PLOS Computational …, 2023 - journals.plos.org
Once challenged by the SARS-CoV-2 virus, the human host immune system triggers a
dynamic process against infection. We constructed a mathematical model to describe host …

Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesis

SQ Du, W Yuan - Journal of medical virology, 2020 - Wiley Online Library
We have applied mathematical modeling to investigate the infections of the ongoing
coronavirus disease‐2019 (COVID‐19) pandemic caused by SARS‐CoV‐2 virus. We first …

A simplified model of the Human Immune System response to the COVID-19

MP Xavier, RF Reis, RW dos Santos… - … on Bioinformatics and …, 2020 - ieeexplore.ieee.org
By November 2020, the Coronavirus disease 2019 (COVID-19) has infected more than 50
million people worldwide, causing more than 1.2 million deaths. This new contagious …

From Infection to Immunity: Understanding the Response to SARS-CoV2 Through In-Silico Modeling

F Castiglione, D Deb, AP Srivastava, P Liò… - Frontiers in …, 2021 - frontiersin.org
Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …

Impairment of T cells' antiviral and anti-inflammation immunities may be critical to death from COVID-19

L Zhang, R Li, G Song… - Royal Society Open …, 2021 - royalsocietypublishing.org
Clarifying dominant factors determining the immune heterogeneity from non-survivors to
survivors is crucial for developing therapeutics and vaccines against COVID-19. The main …

Within host dynamics of SARS-CoV-2 in humans: Modeling immune responses and antiviral treatments

I Ghosh - SN Computer Science, 2021 - Springer
In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and
propagated worldwide as a pandemic, resulting in about 3–5% mortality. Mathematical …

Modeling the viral dynamics of SARS-CoV-2 infection

S Wang, Y Pan, Q Wang, H Miao, AN Brown… - Mathematical …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the
infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading …

Modeling the within-host dynamics of SARS-CoV-2 infection based on antiviral treatment

T Song, Y Wang, X Gu, S Qiao - Mathematics, 2023 - mdpi.com
The COVID-19 pandemic has highlighted the profound impact of the SARS-CoV-2 virus as a
significant threat to human health. There is an urgent need to develop a comprehensive …

[PDF][PDF] Mathematical modelling of COVID-19 disease dynamics: Interaction between immune system and SARS-CoV-2 within host

S Chowdhury, JT Chowdhury, SF Ahmed… - AIMS …, 2022 - researchgate.net
SARS-COV-2 (Coronavirus) viral growth kinetics within-host become a key fact to
understand the COVID-19 disease progression and disease severity since the year 2020 …

In-host mathematical modelling of COVID-19 in humans

EA Hernandez-Vargas, JX Velasco-Hernandez - Annual reviews in control, 2020 - Elsevier
COVID-19 pandemic has underlined the impact of emergent pathogens as a major threat to
human health. The development of quantitative approaches to advance comprehension of …