[HTML][HTML] Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an …
Background Tranexamic acid reduces surgical bleeding and reduces death due to bleeding
in patients with trauma. Meta-analyses of small trials show that tranexamic acid might …
in patients with trauma. Meta-analyses of small trials show that tranexamic acid might …
HALT-IT-tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial
Background Gastrointestinal bleeding is a common emergency that causes substantial
mortality worldwide. Acute upper and lower gastrointestinal bleeding accounts for about …
mortality worldwide. Acute upper and lower gastrointestinal bleeding accounts for about …
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
Crash-2 Collaborators - The Lancet, 2011 - Elsevier
BACKGROUND: The aim of the CRASH-2 trial was to assess the effects of early
administration of tranexamic acid on death, vascular occlusive events, and blood transfusion …
administration of tranexamic acid on death, vascular occlusive events, and blood transfusion …
Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial
Objectives To examine whether the effect of tranexamic acid on the risk of death and
thrombotic events in patients with traumatic bleeding varies according to baseline risk of …
thrombotic events in patients with traumatic bleeding varies according to baseline risk of …
Tranexamic acid for upper gastrointestinal bleeding
C Bennett, SL Klingenberg… - Cochrane Database …, 2014 - cochranelibrary.com
Background Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a
previous version of the present review, we found that tranexamic acid may reduce mortality …
previous version of the present review, we found that tranexamic acid may reduce mortality …
Tranexamic acid for upper gastrointestinal bleeding
LL Gluud, SL Klingenberg… - Cochrane Database of …, 2012 - cochranelibrary.com
Background Tranexamic acid reduces haemorrhage through its antifibrinolytic effects. In a
previous version of the present review, we found that tranexamic acid may reduce mortality …
previous version of the present review, we found that tranexamic acid may reduce mortality …
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from …
Background The CRASH-2 trial showed that early administration of tranexamic acid (TXA)
safely reduces mortality in bleeding in trauma patients. Based on data from the CRASH-2 …
safely reduces mortality in bleeding in trauma patients. Based on data from the CRASH-2 …
Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial
Objective To assess the cost effectiveness of giving tranexamic acid (TXA) to bleeding
trauma patients in low, middle and high income settings. Methods The CRASH-2 trial …
trauma patients in low, middle and high income settings. Methods The CRASH-2 trial …
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion …
Background Each year, worldwide, about 3 million people die as a result of trauma, many
after reaching hospital. Among trauma patients who do survive to reach hospital, bleeding is …
after reaching hospital. Among trauma patients who do survive to reach hospital, bleeding is …
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant hemorrhage (CRASH-2): a randomized …
H Shakur, I Roberts - 50 Landmark Papers every Trauma …, 2019 - api.taylorfrancis.com
This important paper addressed a key clinical question, which was exceptionally novel at the
time of investigation. Namely, could the early administration of 1 gram of tranexamic acid …
time of investigation. Namely, could the early administration of 1 gram of tranexamic acid …
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