[HTML][HTML] A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

JD Mosley, CM Shaffer, SL Van Driest… - The …, 2016 - nature.com
The most common side effect of angiotensin-converting enzyme inhibitor (ACEi) drugs is
cough. We conducted a genome-wide association study (GWAS) of ACEi-induced cough …

Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population

P Hallberg, M Persson, T Axelsson, M Cavalli… - …, 2017 - Future Medicine
Aim: We conducted a genome-wide association study on angiotensin-converting enzyme
inhibitor-induced cough and used our dataset to replicate candidate genes identified in …

Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough

A Grilo, MP Sáez-Rosas, J Santos-Morano… - Pharmacogenetics …, 2011 - journals.lww.com
Methods We carried out a monogenic association analysis of 39 polymorphisms and
haplotypes in genes encoding key proteins related to ACEi activity with the occurrence of …

Association between genetic polymorphisms and angiotensin-converting enzyme inhibitor-induced cough: a systematic review and meta-analysis

G Mu, Q Xiang, S Zhou, Q Xie, Z Liu, Z Zhang… - …, 2019 - Future Medicine
Aim: Genetic polymorphisms may influence the incidence of angiotensin-converting enzyme
(ACE) inhibitor-induced cough. This study aims to investigate this association. Methods: Ten …

Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: the role of: ACE:: ABO:, and: BDKRB2: genes

S Mas, P Gassò, S Alvarez, J Ortiz… - Pharmacogenetics …, 2011 - journals.lww.com
Methods A total of 281 patients who had been treated with ACEi were retrospectively
recruited [102 patients were considered as cases (cough) and 179 patients were considered …

Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci

J Ghouse, V Tragante, A Muhammad… - European Heart …, 2022 - academic.oup.com
Aims To search for sequence variants associated with ACEi discontinuation and to test their
association with ACEi-associated adverse drug reactions (ADRs). Methods and results A …

[HTML][HTML] Angiotensin-converting enzyme and bradykinin gene polymorphisms and cough: a meta-analysis

K Nishio, S Kashiki, H Tachibana… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To evaluate the association between genetic polymorphisms and angiotensin
converting enzyme inhibitor (ACEI)-related cough, and the race-or ethnicity-related …

[HTML][HTML] Angiotensin-converting enzyme (ACE) gene insertion/deletion polymorphism and ACE inhibitor-related cough: a meta-analysis

YF Li, XM Zhu, F Liu, CS Xiao, YF Bian, H Li, J Cai… - PloS one, 2012 - journals.plos.org
Objective An insertion/deletion (I/D) variant in the angiotensin-converting enzyme (ACE)
gene was associated with ACE inhibitor (ACEI)–related cough in previous studies. However …

Angiotensin-converting enzyme (ACE) I/D and bradykinin B2 receptor T/C genes polymorphism in patients with ACE inhibitors-related cough

MS Rohman, JK Fajar, BH Kuncahyo, L Yunita… - Egyptian Journal of …, 2018 - ajol.info
Background: Angiotensin-converting enzyme (ACE) inhibitors-related cough had been
reported to contribute for discontinuation of ACE inhibitors therapy. The role of ACE I/D and …

Polymorphisms in the neurokinin‐2 receptor gene are associated with angiotensin‐converting enzyme inhibitor‐induced cough

TB Kim, SY Oh, HK Park, SG Jeon… - Journal of clinical …, 2009 - Wiley Online Library
Background and objective: Treatment with angiotensin‐converting enzyme (ACE) inhibitors
can induce chronic cough in many patients. Genetic variations in the neurokinin 2 receptor …