Nutrient-sensing mechanisms and pathways

A Efeyan, WC Comb, DM Sabatini - Nature, 2015 - nature.com
The ability to sense and respond to fluctuations in environmental nutrient levels is a requisite
for life. Nutrient scarcity is a selective pressure that has shaped the evolution of most cellular …

Nutrient acquisition strategies of mammalian cells

W Palm, CB Thompson - Nature, 2017 - nature.com
Mammalian cells are surrounded by diverse nutrients, such as glucose, amino acids, various
macromolecules and micronutrients, which they can import through transmembrane …

Neuronal regulation of homeostasis by nutrient sensing

TKT Lam - Nature medicine, 2010 - nature.com
In type 2 diabetes and obesity, the homeostatic control of glucose and energy balance is
impaired, leading to hyperglycemia and hyperphagia. Recent studies indicate that nutrient …

Closing yield gaps through nutrient and water management

ND Mueller, JS Gerber, M Johnston, DK Ray… - Nature, 2012 - nature.com
In the coming decades, a crucial challenge for humanity will be meeting future food
demands without undermining further the integrity of the Earth's environmental systems …

Response of the microbiome–gut–brain axis in Drosophila to amino acid deficit

B Kim, MI Kanai, Y Oh, M Kyung, EK Kim, IH Jang… - Nature, 2021 - nature.com
A balanced intake of macronutrients—protein, carbohydrate and fat—is essential for the well-
being of organisms. An adequate calorific intake but with insufficient protein consumption …

Central nervous system control of food intake

MW Schwartz, SC Woods, D Porte Jr, RJ Seeley… - Nature, 2000 - nature.com
New information regarding neuronal circuits that control food intake and their hormonal
regulation has extended our understanding of energy homeostasis, the process whereby …

Extending healthy life span—from yeast to humans

L Fontana, L Partridge, VD Longo - science, 2010 - science.org
When the food intake of organisms such as yeast and rodents is reduced (dietary restriction),
they live longer than organisms fed a normal diet. A similar effect is seen when the activity of …

Neurons for hunger and thirst transmit a negative-valence teaching signal

JN Betley, S Xu, ZFH Cao, R Gong, CJ Magnus, Y Yu… - Nature, 2015 - nature.com
Homeostasis is a biological principle for regulation of essential physiological parameters
within a set range. Behavioural responses due to deviation from homeostasis are critical for …

[HTML][HTML] The food crisis isn't over

J Von Braun - Nature, 2008 - nature.com
The food crisis isn't over | Nature Skip to main content Thank you for visiting nature.com. You are
using a browser version with limited support for CSS. To obtain the best experience, we …

The disappearing nutrient

Y Ar - Nature, 2009 - nature.com
(Gt= gigatonnes) academics and other minerals specialists to collect extensive data on how
much phosphate there is, how pure it is, what might be available in the future and the useful …