Context: Loss of the thyroid hormone receptor is common in tumors. In mouse models, a
truncated THRB gene leads to thyroid cancer. Previously, we observed up-regulation of the …

Retinoic acid is a promising tool in adjuvant cancer therapies, including refractory thyroid
cancer, and its biological role is mediated by the retinoic acid receptor beta (RARβ) …

MicroRNAs (miRNAs) are a class of short endogenous non-coding RNAs regulating gene
expression in many biological processes, including proliferation, apoptosis and …

MicroRNAs (miRNAs) are endogenous noncoding RNAs that negatively regulate gene
expression by binding the 3′ noncoding region of the messenger RNA targets inducing …

Abstract microRNAs, short non-coding RNAs, influence key physiological processes,
including hormonal regulation, by affecting the expression of genes. In this study we …

TSH is a major regulator of thyroid cell growth and endocrine function. It is known that cAMP
and phosphatidylinositol 3-kinase (PI3K) are responsible for mediating the action of TSH …

Thyroid cancer is one of the most common malignancies of the endocrine system with
increasing incidence. The vast majority of thyroid carcinomas derive from thyroid hormone …

Context: Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy. It
has been demonstrated that micro-RNAs (miRNAs) are involved in the development of PTC …

MicroRNAs (miRNAs) are small noncoding RNAs that post-transcriptionally repress gene
expression by binding generally to the 3′-untranslated regions of their target mRNAs …

Context: Although the pathogenesis of follicular thyroid carcinoma (FTC) and its relation to
follicular adenoma (FA) remains unclear, detailed understanding of FTC carcinogenesis …