The mystery of tuberculosis pathogenesis from the perspective of T regulatory cells

M Keikha, S Soleimanpour, M Eslami, B Yousefi… - Meta Gene, 2020 - Elsevier
It must be admitted that Mycobacterium tuberculosis (Mtb) is one of the worst
microorganisms in nature. This bacterium causes tuberculosis (TB) disease, as a terrible …

Regulation of immunity to tuberculosis

S Brighenti, DJ Ordway - Tuberculosis and the Tubercle …, 2017 - Wiley Online Library
Homeostasis in the immune system has the essential function to minimize deleterious
immune‐mediated inflammation caused by commensal microorganisms, immune responses …

[PDF][PDF] Innate and acquired response on tuberculosis

E Kulchavenya - J Clin Cell Immunol S, 2013 - researchgate.net
Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent; nevertheless, the infection of human organism with Mycobacterium …

T regulatory cells: Achilles' heel of Mycobacterium tuberculosis infection?

O Parkash, S Agrawal, M Madhan Kumar - Immunologic research, 2015 - Springer
T regulatory cells (Treg) constitute a specialized subset of T cells that play a pivotal role in
preventing the occurrence of autoimmune diseases by suppressing deleterious activities of …

Mycobacterium tuberculosis infection: Participation of TH1, TH2, TH17 and regulatory T cells in the immune response

GFF Soto, NV Cedeño, CA de Fernández… - Acta Medica …, 2018 - acta.tums.ac.ir
Mycobacterium tuberculosis, the etiologic agent of Tuberculosis, is a pathogen that is widely
distributed geographically. Tuberculosis is classified as a granulomatous inflammatory …

[PDF][PDF] Cross-talk between the immune system and tuberculosis pathogenesis; a review with emphasis on the immune based treatment

MR Javan, S Shahraki, A Safa, H Aali… - International Journal of …, 2016 - ijbsm.zbmu.ac.ir
As a globally major health problem, tuberculosis (TB) causes almost two million cases of
death annually. Epidemiological studies demonstrate that a third of the world's individuals is …

Understanding the early host immune response against Mycobacterium tuberculosis

B Jee - Central European Journal of Immunology, 2020 - termedia.pl
Generation of immune response is a crucial activity of host defense against any microbial
attack. When facultative organism Mycobacterium tuberculosis (MTB) invades its host …

Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis

ND Marin, SC París, VM Vélez, CA Rojas, M Rojas… - Tuberculosis, 2010 - Elsevier
Regulatory T cells (Tregs) play an essential role in immune homeostasis. In infectious
diseases Tregs may inhibit protective responses facilitating pathogen multiplication and …

[HTML][HTML] Mycobacterium tuberculosis and host interactions in the manifestation of tuberculosis

S Abbasnia, AMH Asnaashari, H Sharebiani… - Journal of Clinical …, 2024 - Elsevier
The final step of epigenetic processes is changing the gene expression in a new
microenvironment in the body, such as neuroendocrine changes, active infections …

Emerging patterns of regulatory T cell function in tuberculosis

A Ahmed, A Vyakarnam - Clinical & Experimental Immunology, 2020 - academic.oup.com
Tuberculosis (TB) is one of the top 10 causes of mortality worldwide from a single infectious
agent and has significant implications for global health. A major hurdle in the development …