Menopause Status and Within-Group Differences in Chronological Age Affect the Functional Neural Correlates of Spatial Context Memory in Middle-Aged Females

A Crestol, S Rajagopal, R Lissaman… - Journal of …, 2023 - Soc Neuroscience
Reductions in the ability to encode and retrieve past experiences in rich spatial contextual
detail (episodic memory) are apparent by midlife—a time when most females experience …

Sex differences in the neural correlates of spatial context memory decline in healthy aging

S Subramaniapillai, S Rajagopal, A Elshiekh… - Journal of cognitive …, 2019 - direct.mit.edu
Aging is associated with episodic memory decline and alterations in memory-related brain
function. However, it remains unclear if age-related memory decline is associated with …

Impact of sex and menopausal status on episodic memory circuitry in early midlife

EG Jacobs, BK Weiss, N Makris… - Journal of …, 2016 - Soc Neuroscience
Cognitive neuroscience of aging studies traditionally target participants age 65 and older.
However, epidemiological surveys show that many women report increased forgetfulness …

[HTML][HTML] Menopause status-and sex-related differences in age associations with spatial context memory and white matter microstructure at midlife

R Lissaman, S Rajagopal, J Kearley, S Pasvanis… - Neurobiology of …, 2024 - Elsevier
Decline in spatial context memory emerges in midlife, the time when most females transition
from pre-to post-menopause. Recent evidence suggests that, among post-menopausal …

Context memory decline in middle aged adults is related to changes in prefrontal cortex function

D Kwon, D Maillet, S Pasvanis, E Ankudowich… - Cerebral …, 2016 - academic.oup.com
The ability to encode and retrieve spatial and temporal contextual details of episodic
memories (context memory) begins to decline at midlife. In the current study, event-related …

Reorganization of functional networks in verbal working memory circuitry in early midlife: the impact of sex and menopausal status

EG Jacobs, B Weiss, N Makris… - Cerebral …, 2017 - academic.oup.com
Converging preclinical and human evidence indicates that the decline in ovarian estradiol
production during the menopausal transition may play a mechanistic role in the neuronal …

Age-and episodic memory-related differences in task-based functional connectivity in women and men

S Subramaniapillai, S Rajagopal… - Journal of cognitive …, 2022 - direct.mit.edu
Aging is associated with episodic memory decline and changes in functional brain
connectivity. Understanding whether and how biological sex influences age-and memory …

Impact of sex and reproductive status on memory circuitry structure and function in early midlife using structural covariance analysis

J Seitz, M Kubicki, EG Jacobs… - Human brain …, 2019 - Wiley Online Library
Research on age‐related memory alterations traditionally targets individuals aged≥ 65
years. However, recent studies emphasize the importance of early aging processes. We …

Ageing-related changes of neural activity associated with spatial contextual memory

J Kukolja, CM Thiel, M Wilms, S Mirzazade… - Neurobiology of …, 2009 - Elsevier
Neuropsychological studies provide evidence for an ageing-related decline of memory for
contextual information related to remembered items. Using event-related fMRI we …

Longitudinal characterization and biomarkers of age and sex differences in the decline of spatial memory

M Febo, A Rani, B Yegla, J Barter, A Kumar… - Frontiers in Aging …, 2020 - frontiersin.org
The current longitudinal study examined factors (sex, physical function, response to novelty,
ability to adapt to a shift in light/dark cycle, brain connectivity), which might predict the …