Recent data suggest that gut-associated lymphoid tissue (GALT) plays a major role in the development of immunoglobulin A (IgA) nephropathy (IgAN). A genome-wide association …
Abstract Links between IgA nephropathy (IgAN) and the mucosa have been recognized since the 1970s. In particular, the observation of visible haematuria induced by respiratory …
C Papista, S Lechner, SB Mkaddem, MB LeStang… - Kidney international, 2015 - Elsevier
IgA1 complexes containing deglycosylated IgA1, IgG autoantibodies, and a soluble form of the IgA receptor (sCD89), are hallmarks of IgA nephropathy (IgAN). Food antigens, notably …
R Coppo - Nephrology Dialysis Transplantation, 2015 - academic.oup.com
It is commonly stated that mucosal immunity plays a role in the pathogenesis of IgA nephropathy (IgAN); however, the search for specific eliciting factors has been largely …
Immunoglobulin A nephropathy (IgAN) or Berger's disease is the most common form of primary glomerulonephritis in the world and one of the first causes of end-stage renal failure …
R Coppo - Nephrologie & therapeutique, 2018 - Elsevier
IgA nephropathy, identified 50 years ago in France, is the most frequent glomerular disease worldwide. The course is variable, but in most of the cases there is a relentless decline in …
HK Smerud, P Bárány, K Lindström… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. Systemic corticosteroid treatment has been shown to exert some protection against renal deterioration in IgA nephropathy (IgAN) but is not commonly recommended for …
J Barratt, BH Rovin, D Cattran, J Floege… - Kidney International …, 2020 - kireports.org
It is more than 50 years since the first description of IgA nephropathy (IgAN) by the Parisian pathologist, Jean Berger. 1 Over this time, IgAN became recognized as the most common …
C Reily, H Ueda, ZQ Huang, J Mestecky… - Journal of …, 2014 - Wiley Online Library
Immunoglobulin A (IgA) nephropathy (IgAN), the leading cause of primary glomerulonephritis, is characterized by IgA1‐containing immunodeposits in the glomeruli …