Prediction and stratification of longitudinal risk for chronic obstructive pulmonary disease across smoking behaviors

Y He, DC Qian, JA Diao, MH Cho, EK Silverman… - Nature …, 2023 - nature.com
Smoking is the leading risk factor for chronic obstructive pulmonary disease (COPD)
worldwide, yet many people who never smoke develop COPD. We perform a longitudinal …

Environmental correlates of chronic obstructive pulmonary disease in 96 779 participants from the UK Biobank: a cross-sectional, observational study

C Sarkar, B Zhang, M Ni, S Kumari… - The Lancet Planetary …, 2019 - thelancet.com
Background The role of environmental exposures in chronic obstructive pulmonary disease
(COPD) remains inconclusive. We examined the association between environmental …

Design of the subpopulations and intermediate outcome measures in COPD (SPIROMICS) AIR study

NN Hansel, LM Paulin, AJ Gassett… - BMJ open …, 2017 - bmjopenrespres.bmj.com
Introduction Population-based epidemiological evidence suggests that exposure to ambient
air pollutants increases hospitalisations and mortality from chronic obstructive pulmonary …

[HTML][HTML] A risk prediction model for mortality among smokers in the COPDGene® study

M Strand, E Austin, M Moll, KA Pratte… - … Diseases: Journal of …, 2020 - ncbi.nlm.nih.gov
Background: Risk factor identification is a proven strategy in advancing treatments and
preventive therapy for many chronic conditions. Quantifying the impact of those risk factors …

Air pollution and risk of chronic obstructed pulmonary disease: The modifying effect of genetic susceptibility and lifestyle

L Wang, J Xie, Y Hu, Y Tian - EBioMedicine, 2022 - thelancet.com
Background The effect of long-term exposure to air pollution on the development of chronic
obstructive pulmonary disease (COPD) is still controversial, and the role of the interactions …

Difficulties identifying and targeting COPD and population-attributable risk of smoking for COPD: a population study

D Wilson, R Adams, S Appleton, R Ruffin - Chest, 2005 - Elsevier
Study objectives Respiratory public health interventions depend on accurate identification of
the target group, yet this may vary depending on the diagnostic criteria used. We therefore …

Prediction of COPD risk accounting for time-varying smoking exposures

JT Chang, R Meza, DT Levy, D Arenberg, J Jeon - PloS one, 2021 - journals.plos.org
Rationale Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of
death in the United States. Studies have primarily assessed the relationship between …

Smoking duration alone provides stronger risk estimates of chronic obstructive pulmonary disease than pack-years

SP Bhatt, Y Kim, KF Harrington, JE Hokanson, SM Lutz… - Thorax, 2018 - thorax.bmj.com
Background Cigarette smoking is the strongest risk factor for COPD. Smoking burden is
frequently measured in pack-years, but the relative contribution of cigarettes smoked per day …

Occupations associated with COPD risk in the large population-based UK Biobank cohort study

S De Matteis, D Jarvis, S Hutchings… - Occupational and …, 2016 - oem.bmj.com
Objectives Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality worldwide. Exposure to occupational hazards is an important preventable risk …

Canadian Cohort Obstructive Lung Disease (CanCOLD): fulfilling the need for longitudinal observational studies in COPD

J Bourbeau, WC Tan, A Benedetti… - COPD: Journal of …, 2014 - Taylor & Francis
Awareness, diagnosis and treatment of COPD, compared to other major causes of death,
remains far too low. This article describes the protocol objectives, design and the …