Pseudomonas aeruginosa is a leading cause of corneal infection both within India and
globally, often causing a loss of vision. Increasing antimicrobial resistance among the …

Staphylococcus aureus is one of the primary causative agents of skin and wound infections.
As bacterial adherence is essential for infection, blocking this step can reduce invasion of …

purpose. To determine the effects of blocking substance P (SP) interactions with its major
receptor (NK1-R) using the antagonist spantide I in susceptible mice infected with …

Pseudomonas aeruginosa is an opportunistic pathogen and is the major cause of corneal
infections in India and worldwide. The increase in antimicrobial resistance among …

Pseudomonas aeruginosa (PA) is the leading cause of corneal blindness worldwide. A
constant increase in multi-drug resistant PA strains have heightened the challenge of …

The corneal epithelium is a layer in the anterior part of eye that contributes to light refraction
onto the retina and to the ocular immune defense. Although an intact corneal epithelium is …

Pseudomonas aeruginosa is the primary bacterial pathogen causing contact lens related
keratitis. Available ophthalmic agents have reduced efficacy and antimicrobial peptides …

Many microbial pathogens subvert cell surface heparan sulfate proteoglycans (HSPGs) to
infect host cells in vitro. The significance of HSPG-pathogen interactions in vivo, however …

Bacterial keratitis (BK) is a major cause of corneal blindness globally. This study aimed to
develop a novel class of antimicrobial therapy, based on human-derived hybrid host …

CAP37, a protein constitutively expressed in human neutrophils and induced in response to
infection in corneal epithelial cells, plays a significant role in host defense against infection …