Many experimental data have suggested that the renin-angiotensin system participates in
immune and inflammatory responses. Angiotensin II is involved in several steps of the …

Blockers of the renin-angiotensin system are used in the treatment of several cardiovascular
and renal diseases, including hypertension, atherosclerosis, and cardiac failure …

Angiotensin II (AngII) participates in the pathogenesis of renal diseases, through the
regulation of two key processes inflammation and fibrosis. AT1 and AT2 are the main …

Angiotensin II (AngII), the major effector peptide of renin–angiotensin system (RAS), is now
recognized as a growth factor that regulates cell growth and fibrosis, besides being a …

That the renin–angiotensin system (RAS) is involved in regulation of blood pressure,
vasoconstriction, sodium intake and potassium excretion is well established. Studies in the …

Inflammation, oxidative stress and hypertension are closely interrelated. Here we discuss
the (patho) physiology of vascular inflammation in hypertension, focusing specifically on the …

Abstract Purpose of Review Mechanisms facilitating progression of hypertension via cross
stimulation of the renin-angiotensin system (RAS) and inflammation have been proposed …

Abstract Angiotensin II (Ang II) increases adhesion molecules, cytokines and chemokines
and exerts a proinflammatory effect on leucocytes, endothelial cells and vascular smooth …

Pathogenesis of the atherosclerotic process is deemed as multi-factorial, and characterized
by chronic inflammatory response. Although hypertension is known to be one of the most …

Vascular injury, characterized by endothelial dysfunction, structural remodelling,
inflammation and fibrosis, plays an important role in cardiovascular diseases. Cellular …