Over the past decade, the treatment landscape for patients with metastatic renal cell
carcinoma (RCC) has evolved dramatically. The therapeutic options available have …

The management of patients with metastatic renal cell carcinoma (RCC) has changed
dramatically over the past few years. Nephrectomy remains an important intervention for …

Renal cell carcinomas vary considerably in their tumor biology and disease course, which is
reflected in the range of treatment paradigms in localized and metastatic renal cell …

Renal cell carcinoma (RCC) is not a single entity but includes various tumor subtypes that
have been identified on the basis of either characteristic pathologic features or distinctive …

The armamentarium for the systemic therapy of advanced renal cell carcinoma (RCC) has
undergone dramatic changes over the past 6 years. While high-dose interleukin (IL)-2 …

Importance The treatment landscape of metastatic renal cell carcinoma has evolved rapidly
over the last decade. Recent combination approaches heralded by targeting immune …

Oncologic treatments for renal cell carcinoma (RCC) have undergone a major revolution in
the past 2 decades, moving away from the pre-2004 Dark Age during which interleukin 2 …

During the last decade, the treatment of advanced or metastatic renal cell carcinoma (RCC)
was revolutionised with the advent of antiangiogenic drugs and tyrosine-kinase inhibitors …

The treatment of patients with renal cell carcinoma (RCC) is evolving rapidly, with promising
new regimens being developed and approved for patients with advanced disease …

Purpose To outline current practices and challenges in the systemic management of patients
with advanced renal cell carcinoma (RCC). Design We conducted a focused review of …