Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics

L Geurts, AM Neyrinck, NM Delzenne… - Beneficial …, 2014 - wageningenacademic.com
Crosstalk between organs is crucial for controlling numerous homeostatic systems (eg
energy balance, glucose metabolism and immunity). Several pathological conditions, such …

The gut microbiome as therapeutic target

PD Cani, NM Delzenne - Pharmacology & therapeutics, 2011 - Elsevier
Obesity, type-2 diabetes and low-grade inflammation are becoming worldwide epidemics. In
this regard, the literature provides a novel concept that we call “MicrObesity”(Microbes and …

The gut microbiota, obesity and insulin resistance

J Shen, MS Obin, L Zhao - Molecular aspects of medicine, 2013 - Elsevier
The human gut is densely populated by commensal and symbiotic microbes (the “gut
microbiota”), with the majority of the constituent microorganisms being bacteria …

Beyond gut microbiota: understanding obesity and type 2 diabetes

E Lau, D Carvalho, C Pina-Vaz, JA Barbosa, P Freitas - Hormones, 2015 - Springer
Obesity and type 2 diabetes are metabolic diseases that have reached epidemic proportions
worldwide. Although their etiology is complex, both result from interplay between behaviour …

The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus

RS Kootte, A Vrieze, F Holleman… - Diabetes, Obesity …, 2012 - Wiley Online Library
Obesity and type 2 diabetes mellitus (T2DM) are attributed to a combination of genetic
susceptibility and lifestyle factors. Their increasing prevalence necessitates further studies …

Influence of gut microbiota on subclinical inflammation and insulin resistance

BM Carvalho, MJ Abdalla Saad - Mediators of inflammation, 2013 - Wiley Online Library
Obesity is the main condition that is correlated with the appearance of insulin resistance,
which is the major link among its comorbidities, such as type 2 diabetes, nonalcoholic fatty …

Interplay between obesity and associated metabolic disorders: new insights into the gut microbiota

PD Cani, NM Delzenne - Current opinion in pharmacology, 2009 - Elsevier
Obesity and associated metabolic disorders are worldwide epidemic. The literature provides
new evidence that gut microbiota dysbiosis (at the phyla, genus, or species level) affects …

[HTML][HTML] Diabetes, obesity and gut microbiota

A Everard, PD Cani - Best practice & research Clinical gastroenterology, 2013 - Elsevier
The gut microbiota composition has been associated with several hallmarks of metabolic
syndrome (eg, obesity, type 2 diabetes, cardiovascular diseases, and non-alcoholic …

Do nutrient–gut–microbiota interactions play a role in human obesity, insulin resistance and type 2 diabetes?

M Diamant, EE Blaak, WM De Vos - Obesity reviews, 2011 - Wiley Online Library
The current obesity and type 2 diabetes pandemics have causes beyond changes in eating
and exercise habits against a susceptible genetic background. Gut bacteria seem to …

Interactions between gut microbiota and host metabolism predisposing to obesity and diabetes

G Musso, R Gambino, M Cassader - Annual review of medicine, 2011 - annualreviews.org
Novel, culture-independent, molecular and metagenomic techniques have provided new
insight into the complex interactions between the mammalian host and gut microbial …