The carbon− carbon triple bond of alkynes is one of the basic functional groups, its reactions
belonging to the foundations of organic chemistry. In the past decades, acetylene chemistry …

Palladium-catalyzed cross-coupling reactions, especially those involving Zn, Al, Zr (Negishi
coupling), and B (Suzuki coupling), collectively have brought about “revolutionary” changes …

Several Pd-catalyzed cross-coupling procedures for the synthesis of alkynes were reported
in the mid 1970s. 1-5 Of these, the Sonogashira protocol3 involving the treatment of terminal …

General protocols for the palladium-catalyzed coupling of aryl chlorides and alkynes and
aryl tosylates and alkynes were developed. Addition of a copper cocatalyst can inhibit …

Phosphane-free oxime-derived palladacycle 2 is an efficient precatalyst for the copper-free
acylation of terminal alkynes with different carboxylic acid chlorides in toluene in the …

In this paper we report a brief review of the palladium–catalyzed olefination and amination of
aryl chlorides. Special emphasis is given on the efficiency of known catalysts. Best turnover …

The development of addition reactions wherein the product is the simple sum of the
reactants plus anything else (only needed catalytically) constitutes an important goal for …

In this chapter the authors discuss the Pd‐catalyzed reactions of aryl, alkenyl, benzyl, alkyl,
and acyl electrophiles with metal nucleophiles leading to carbon‐metal bond formation. The …

Conjugated alkynes are recurring building blocks in natural products, a wide range of
industrial intermediates, pharmaceuticals and agrochemicals, and molecular materials for …

Studies on the palladium-catalyzed formation of aryl amines, aryl ethers and a-aryl carbonyl
compounds from aryl halides are reported. These studies range from synthetic methodology …