Immune-checkpoint inhibitors from cancer to COVID‑19: A promising avenue for the treatment of patients with COVID‑19

S Vivarelli, L Falzone, F Torino… - International …, 2021 - spandidos-publications.com
The severe acute respiratory syndrome associated coronavirus‑2 (SARS‑CoV‑2) poses a
threat to human life worldwide. Since early March, 2020, coronavirus disease 2019 (COVID …

Immune checkpoint inhibitors for cancer therapy in the COVID-19 era

M Maio, O Hamid, J Larkin, A Covre, M Altomonte… - Clinical Cancer …, 2020 - AACR
The potential immune intersection between COVID-19 disease and cancer therapy raises
important practical clinical questions and highlights multiple scientific gaps to be filled …

Do checkpoint inhibitors compromise the cancer patients' immunity and increase the vulnerability to COVID-19 infection?

J Kattan, C Kattan, T Assi - Immunotherapy, 2020 - Future Medicine
The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has been declared a
pandemic by the WHO that claimed the lives of thousands of people within a few months …

[HTML][HTML] COVID-19 and immune checkpoint inhibitors: initial considerations

RJ Sullivan, DB Johnson, BI Rini… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
COVID-19 infections are characterized by inflammation of the lungs and other organs that
ranges from mild and asymptomatic to fulminant and fatal. Patients who are …

Cancer management during COVID-19 pandemic: is immune checkpoint inhibitors-based immunotherapy harmful or beneficial?

S Vivarelli, L Falzone, CM Grillo, G Scandurra, F Torino… - Cancers, 2020 - mdpi.com
The coronavirus disease 2019 (COVID-19) is currently representing a global health threat
especially for fragile individuals, such as cancer patients. It was demonstrated that cancer …

[HTML][HTML] Immune checkpoint inhibitors: a physiology-driven approach to the treatment of coronavirus disease 2019

S Di Cosimo, A Malfettone, JM Pérez-García… - European Journal of …, 2020 - Elsevier
While confirmed cases of the deadly coronavirus disease 2019 (COVID-19) have exceeded
4.7 million globally, scientists are pushing forward with efforts to develop vaccines and …

Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors

M Bersanelli - Immunotherapy, 2020 - Future Medicine
Conclusion Clinical decisions about cancer patients deserving immunotherapy in the current
context of the COVID-19 pandemic should be characterized by separated reflections …

Immune checkpoint inhibition in COVID-19: risks and benefits

PS Pezeshki, N Rezaei - Expert Opinion on Biological Therapy, 2021 - Taylor & Francis
Introduction Immune checkpoint inhibition (ICI) is a novel cancer immunotherapy, which is
administered in patients with metastatic, refractory, or relapsed solid cancer types. Since the …

At the crossroads: COVID-19 and immune-checkpoint blockade for cancer

MC Garassino, A Ribas - Cancer immunology research, 2021 - AACR
The immunomodulatory effects of immune-checkpoint blockade (ICB) therapy for cancer
may act at the crossroads between the need to increase antiviral immune responses to …

Italian survey on managing immune checkpoint inhibitors in oncology during COVID‐19 outbreak

M Tagliamento, F Spagnolo, F Poggio… - European Journal of …, 2020 - Wiley Online Library
Background During COVID‐19 outbreak, oncological care has been reorganized. Patients
with cancer have been reported to experience a more severe COVID‐19 syndrome; …