Taurine and oxidative stress in retinal health and disease

V Castelli, A Paladini, M d'Angelo… - CNS neuroscience & …, 2021 - Wiley Online Library
Retinal disorders are leading causes of blindness and are due to an imbalance between
reactive oxygen species and antioxidant scavenger (in favor of pro‐oxidant species) or a …

Taurine: A promising nutraceutic in the prevention of retinal degeneration

D García-Ayuso, J Di Pierdomenico… - Neural Regeneration …, 2023 - journals.lww.com
Taurine is considered a non-essential amino acid because it is synthesized by most
mammals. However, dietary intake of taurine may be necessary to achieve the physiological …

Taurine: the comeback of a neutraceutical in the prevention of retinal degenerations

N Froger, L Moutsimilli, L Cadetti, F Jammoul… - Progress in retinal and …, 2014 - Elsevier
Taurine is the most abundant amino acid in the retina. In the 1970s, it was thought to be
involved in retinal diseases with photoreceptor degeneration, because cats on a taurine-free …

Dietary taurine reduces retinal damage produced by photochemical stress via antioxidant and anti-apoptotic mechanisms in Sprague–Dawley rats

X Yu, K Chen, N Wei, Q Zhang, J Liu… - British journal of nutrition, 2007 - cambridge.org
Taurine has been shown to be tissue protective in many models of oxidant-induced injury.
However, its protective role against retinal damage induced by photochemical stress is less …

Age-related retinal degeneration in animal models of aging: possible involvement of taurine deficiency and oxidative stress

J Militante, JB Lombardini - Neurochemical research, 2004 - Springer
There is strong evidence that the retina degenerates with age. Electroretinogram deficits and
photoreceptor cell death and structural abnormalities have been observed in both animal …

Systemic taurine treatment provides neuroprotection against retinal photoreceptor degeneration and visual function impairments

Y Tao, M He, Q Yang, Z Ma, Y Qu, W Chen… - Drug Design …, 2019 - Taylor & Francis
Objective Retinitis pigmentosa causes progressive photoreceptor degeneration in the
subjects while no clinical therapy exists. The present study sought to evaluate the potential …

Chronic taurine supplementation ameliorates oxidative stress and Na + K + ATPase impairment in the retina of diabetic rats

MAS Di Leo, SA Santini, S Cercone, D Lepore… - Amino acids, 2002 - Springer
This study evaluates the effect of 4 months supplementation with 2% and 5% taurine (w/w)
on the retina of diabetic rats. In non-diabetic rats, taurine does not modify glycemia, body …

Taurine protects against NMDA-induced retinal damage by reducing retinal oxidative stress

AJA Jafri, R Agarwal, I Iezhitsa, P Agarwal, NM Ismail - Amino Acids, 2019 - Springer
This study aimed to evaluate effect of TAU on NMDA-induced changes in retinal redox
status, retinal cell apoptosis and retinal morphology in Sprague–Dawley rats. Taurine was …

Taurine provides neuroprotection against retinal ganglion cell degeneration

N Froger, L Cadetti, H Lorach, J Martins… - PloS one, 2012 - journals.plos.org
Retinal ganglion cell (RGC) degeneration occurs in numerous retinal diseases leading to
blindness, either as a primary process like in glaucoma, or secondary to photoreceptor loss …

Taurine: A source and application for the relief of visual fatigue

H Duan, W Song, J Guo, W Yan - Nutrients, 2023 - mdpi.com
According to reports, supplementation with appropriate doses of taurine may help to reduce
visual fatigue. Presently, some progress has been made in research related to taurine in eye …