purpose. To quantify and evaluate the distribution of angiotensin II (Ang II) and its receptors
in the human retina. methods. Donor eyes were obtained within 12 hours postmortem and …

We investigated the immunohistochemical distribution of 3 components of the renin-
angiotensin system (RAS), angiotensin-converting enzyme (ACE), angiotensin II (AngII) and …

Renin–Angiotensin System is classically recognized for its role in the control of systemic
blood pressure. However, the retina is recognized to have all the components necessary for …

purpose. To investigate the anti-inflammatory and anti-angiogenic effects of telmisartan, an
angiotensin II type 1 receptor (AT1-R) antagonist, on ischemia-induced retinal …

There is evidence that angiotensin II, vascular endothelial growth factor (VEGF),
angiopoietins, and their cognate receptors participate in retinal angiogenesis. We …

Vascular endothelial growth factor (VEGF) is a main stimulator of pathological vessel
formation. Nevertheless, increasing evidence suggests that Angiotensin II (Ang II) can play …

Recent studies have shown that angiopoietins (Angs) and their receptor, Tie2, play a role in
vascular integrity and neovascularization. The renin-angiotensin system has been …

The renin-angiotensin system (RAS) has been traditionally linked to blood pressure and
volume regulation mediated through the angiotensin II (ANG II) type 1 (AT1) receptor. Here …

purpose. To determine the location and activity of renin–angiotensin system (RAS)
components in the developing rat retina and whether the RAS influences retinal …

Abstract Angiotensin II (Ang II) is internalized by various cell types via receptor-mediated
endocytosis. Little is known about the kinetics of this process in the whole animal and about …