The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review

D Bian, Y Wu, G Song, R Azizi, A Zamani - Stem Cell Research & Therapy, 2022 - Springer
Recently, mesenchymal stromal cells (MSCs) and also their exosome has become a game-
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …

MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy

F Marofi, KI Alexandrovna, R Margiana… - Stem Cell Research & …, 2021 - Springer
Currently, mesenchymal stem/stromal stem cell (MSC) therapy has become a promising
option for accelerating cutaneous wound healing. In vivo reports have outlined the robust …

Human mesenchymal stromal cell-derived exosomes promote in vitro wound healing by modulating the biological properties of skin keratinocytes and fibroblasts and …

R Tutuianu, AM Rosca, DM Iacomi… - International Journal of …, 2021 - mdpi.com
Bone marrow-derived mesenchymal stromal cells (MSCs) are major players in regenerative
therapies for wound healing via their paracrine activity, mediated partially by exosomes. Our …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: A novel and potential remedy for cutaneous wound healing and regeneration

JC Hu, CX Zheng, BD Sui, WJ Liu… - World Journal of Stem …, 2022 - ncbi.nlm.nih.gov
Poor healing of cutaneous wounds is a common medical problem in the field of
traumatology. Due to the intricate pathophysiological processes of wound healing, the use of …

MSC-exosome: a novel cell-free therapy for cutaneous regeneration

P Wu, B Zhang, H Shi, H Qian, W Xu - Cytotherapy, 2018 - Elsevier
Cutaneous regeneration is a dynamic and complex process that requires a series of
coordinated interactions involving epidermal cells, dermal cells, growth factors, the …

Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration

P Hu, Q Yang, Q Wang, C Shi, D Wang… - Burns & …, 2019 - academic.oup.com
Cutaneous regeneration at the wound site involves several intricate and dynamic processes
which require a series of coordinated interactions implicating various cell types, growth …

Extracellular vesicles derived from mesenchymal stem cells (MSC) in regenerative medicine: applications in skin wound healing

A Casado-Díaz, JM Quesada-Gómez… - … in Bioengineering and …, 2020 - frontiersin.org
The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …

Advances in mesenchymal stem/stromal cell-based therapy and their extracellular vesicles for skin wound healing

MJ Saadh, AA Ramírez-Coronel, RS Saini… - Human Cell, 2023 - Springer
Wound healing is a dynamic and complicated process containing overlapping phases.
Presently, definitive therapy is not available, and the investigation into optimal wound care is …

[HTML][HTML] The therapeutic potential of MSC-EVs as a bioactive material for wound healing

Y Hou, J Li, S Guan, F Witte - Engineered Regeneration, 2021 - Elsevier
In clinical trials, cell therapy, especially mesenchymal stem cells (MSC), contributed to
wound treatment options in an innovative way. While, there are some limitations of MSC …

Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem Cell Research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …