Many cognitive abilities decline with age even in the absence of detectable pathology.
Recent evidence indicates that age-related neural dedifferentiation, operationalized in terms …

This review focuses on possible contributions of neural dedifferentiation to age-related
cognitive decline. Neural dedifferentiation is held to reflect a breakdown in the functional …

There are substantial declines in behavioral measures of cognitive function with age,
including decreased function of executive processes and long-term memory. There is also …

Healthy aging is associated with decreased neural selectivity (dedifferentiation) in category-
selective cortical regions. This finding has prompted the suggestion that dedifferentiation …

Aging is associated with myriad changes in behavioral performance and brain structure and
function. Given this complex interplay of brain and behavior, two streams of findings are …

It is well established that brain structures and cognitive functions change across the life
span. A long-standing hypothesis called “age differentiation” additionally posits that the …

To explore neural correlates of cognitive decline in aging, we used longitudinal behavioral
data to identify two groups of older adults (n= 40) that differed with regard to whether their …

Defining the neural basis of age-related cognitive dysfunction is a major goal of current
research on aging. Compelling evidence from laboratory animals and humans indicates that …

What is the neurocognitive basis for the considerable individual differences observed in
functioning of the adult mind and brain late in life? We review the evidence that in healthy …

Dedifferentiation, or decreased processing specificity, has been suggested to represent a
ubiquitous characteristic of cognitive aging. In this study, we examined both age-related …