Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements

J Guo, J Li, H Chen, PL Bond, Z Yuan - Water research, 2017 - Elsevier
The intensive use of antibiotics results in their continuous release into the environment and
the subsequent widespread occurrence of antibiotic resistant bacteria (ARB), antibiotic …

Exploring the antibiotic resistome in activated sludge and anaerobic digestion sludge in an urban wastewater treatment plant via metagenomic analysis

K Yoo, H Yoo, J Lee, EJ Choi, J Park - Journal of Microbiology, 2020 - Springer
Antibiotic resistance genes (ARGs) are emerging contaminants that pose a potential threat
to human health worldwide. Urban wastewater treatment plants (WWTPs) are a main source …

Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge

D Dai, C Brown, H Bürgmann, DGJ Larsson, I Nambi… - Microbiome, 2022 - Springer
Background There is concern that the microbially rich activated sludge environment of
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …

[HTML][HTML] Metagenomic profiling and transfer dynamics of antibiotic resistance determinants in a full-scale granular sludge wastewater treatment plant

D Calderón-Franco, R Sarelse, S Christou, M Pronk… - Water Research, 2022 - Elsevier
Abstract In the One Health context, wastewater treatment plants (WWTPs) are central to
safeguarding water resources. Nonetheless, many questions remain about their …

Occurrence of antibiotic resistance genes and multidrug-resistant bacteria during wastewater treatment processes

M Kang, J Yang, S Kim, J Park, M Kim… - Science of the Total …, 2022 - Elsevier
Wastewater treatment plants (WWTPs) constantly receive a wide variety of contaminants,
including pharmaceuticals, and are potential reservoirs of antibiotic resistance genes …

[HTML][HTML] Metagenomic and metatranscriptomic analyses reveal activity and hosts of antibiotic resistance genes in activated sludge

Z Liu, U Klümper, Y Liu, Y Yang, Q Wei, JG Lin… - Environment …, 2019 - Elsevier
Wastewater treatment plants (WWTPs) are a source and reservoir for subsequent spread of
various antibiotic resistance genes (ARGs). However, little is known about the activity and …

Deciphering the mobility and bacterial hosts of antibiotic resistance genes under antibiotic selection pressure by metagenomic assembly and binning approaches

R Zhao, K Yu, J Zhang, G Zhang, J Huang, L Ma… - Water research, 2020 - Elsevier
The presence of antibiotics can exert significant selection pressure on the emergence and
spread of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB) …

Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics

R Zhao, J Feng, J Liu, W Fu, X Li, B Li - Water Research, 2019 - Elsevier
Currently, the effects of high antibiotic concentrations on the performance of microbiota and
antibiotic resistance genes (ARGs) in activated sludge (AS) process are not well …

The prevalence and removal of antibiotic resistance genes in full-scale wastewater treatment plants: Bacterial host, influencing factors and correlation with nitrogen …

Q Ping, Z Zhang, L Ma, T Yan, L Wang, Y Li - Science of The Total …, 2022 - Elsevier
This study investigated the prevalence of antibiotic resistance genes (ARGs) in the influent,
effluent, and waste activated sludge (WAS) of eight full-scale municipal wastewater …

Metagenomic analysis reveals the prevalence and persistence of antibiotic-and heavy metal-resistance genes in wastewater treatment plant

SK Gupta, H Shin, D Han, HG Hur, T Unno - Journal of Microbiology, 2018 - Springer
The increased antibiotic resistance among microorganisms has resulted into growing
interest for investigating the wastewater treatment plants (WWTPs) as they are reported to be …