A clinical update on SARS-CoV-2: Pathology and development of potential inhibitors

DD Singh, I Han, EH Choi, DK Yadav - Current Issues in Molecular …, 2023 - mdpi.com
SARS-CoV-2 (severe acute respiratory syndrome) is highly infectious and causes severe
acute respiratory distress syndrome (SARD), immune suppression, and multi-organ failure …

SARS-CoV-2 therapeutics: how far do we stand from a remedy?

A Singh, V Gupta - Pharmacological Reports, 2021 - Springer
The SARS-CoV-2 has affected millions worldwide and has posed an immediate need for
effective pharmacological interventions. Ever since the outbreak was declared, the medical …

An update on antiviral therapy against SARS-CoV-2: how far have we come?

O Indari, S Jakhmola, E Manivannan… - Frontiers in …, 2021 - frontiersin.org
COVID-19 pandemic has spread worldwide at an exponential rate affecting millions of
people instantaneously. Currently, various drugs are under investigation to treat an …

SARS-CoV-2: repurposed drugs and novel therapeutic approaches—insights into chemical structure—biological activity and toxicological screening

CA Dehelean, V Lazureanu, D Coricovac… - Journal of clinical …, 2020 - mdpi.com
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic represents the
primary public health concern nowadays, and great efforts are made worldwide for efficient …

[HTML][HTML] SARS-CoV-2: from the pathogenesis to potential anti-viral treatments

PK Zarandi, MR Zinatizadeh, M Zinatizadeh… - Biomedicine & …, 2021 - Elsevier
Introduction The world is witnessing the spread of one of the members of Coronaviruses
(CoVs) family, called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the …

Understanding the epidemiology, pathophysiology, diagnosis and management of SARS-CoV-2

AO Fadaka, NRS Sibuyi, OB Adewale… - Journal of …, 2020 - journals.sagepub.com
The emergence of coronavirus disease 2019 (COVID-19) in December 2019 has resulted in
over 20 million cases and 741,808 deaths globally, affecting more than 200 countries …

Therapeutic strategies to fight COVID‐19: Which is the status artis?

C Scavone, A Mascolo, C Rafaniello… - British Journal of …, 2022 - Wiley Online Library
COVID‐19 is a complex disease, and many difficulties are faced today especially in the
proper choice of pharmacological treatments. The role of antiviral agents for COVID‐19 is …

COVID-19: a defining moment for clinical pharmacology?

PH van der Graaf, KM Giacomini - 2020 - cabidigitallibrary.org
Though most drug development takes years from discovery to approval, for the COVID-19
pandemic, drug development is on a fundamentally different timeline. Broadly speaking …

Pharmacological insight into potential therapeutic agents for the deadly Covid-19 pandemic

R Bhandari, G Khanna, A Kuhad - European Journal of Pharmacology, 2021 - Elsevier
Coronaviruses are pleomorphic, enveloped, or spherical viruses, which have a size ranging
from 80 to 120 nm. These viruses act on receptors that cause the triggering of fusion …

Tackling SARS-CoV-2: proposed targets and repurposed drugs

S Joshi, M Joshi, MS Degani - Future medicinal chemistry, 2020 - Taylor & Francis
The SARS-CoV-2 pandemic, declared as a global health emergency by the WHO in
February 2020, has currently infected more than 6 million people with fatalities near 371,000 …