Patterns of shared signatures of recent positive selection across human populations

KE Johnson, BF Voight - Nature ecology & evolution, 2018 - nature.com
Signatures of recent positive selection often overlap across human populations, but the
question of how often these overlaps represent a single ancestral event remains unresolved …

Constructing genomic maps of positive selection in humans: where do we go from here?

JM Akey - Genome research, 2009 - genome.cshlp.org
Identifying targets of positive selection in humans has, until recently, been frustratingly slow,
relying on the analysis of individual candidate genes. Genomics, however, has provided the …

[HTML][HTML] Admixture has obscured signals of historical hard sweeps in humans

Y Souilmi, R Tobler, A Johar, M Williams… - Nature Ecology & …, 2022 - nature.com
The role of natural selection in shaping biological diversity is an area of intense interest in
modern biology. To date, studies of positive selection have primarily relied on genomic …

Genome-wide signals of positive selection in human evolution

D Enard, PW Messer, DA Petrov - Genome research, 2014 - genome.cshlp.org
The role of positive selection in human evolution remains controversial. On the one hand,
scans for positive selection have identified hundreds of candidate loci, and the genome …

Detecting ancient positive selection in humans using extended lineage sorting

S Peyrégne, MJ Boyle, M Dannemann… - Genome …, 2017 - genome.cshlp.org
Natural selection that affected modern humans early in their evolution has likely shaped
some of the traits that set present-day humans apart from their closest extinct and living …

[HTML][HTML] A new approach for using genome scans to detect recent positive selection in the human genome

K Tang, KR Thornton, M Stoneking - PLoS biology, 2007 - journals.plos.org
Genome-wide scanning for signals of recent positive selection is essential for a
comprehensive and systematic understanding of human adaptation. Here, we present a …

Exploring the occurrence of classic selective sweeps in humans using whole-genome sequencing data sets

M Fagny, E Patin, D Enard, LB Barreiro… - Molecular biology …, 2014 - academic.oup.com
Genome-wide scans for selection have identified multiple regions of the human genome as
being targeted by positive selection. However, only a small proportion has been replicated …

[HTML][HTML] Human adaptation and population differentiation in the light of ancient genomes

FM Key, Q Fu, F Romagné, M Lachmann… - Nature …, 2016 - nature.com
The influence of positive selection sweeps in human evolution is increasingly debated,
although our ability to detect them is hampered by inherent uncertainties in the timing of past …

Limited evidence for classic selective sweeps in African populations

JM Granka, BM Henn, CR Gignoux, JM Kidd… - Genetics, 2012 - academic.oup.com
While hundreds of loci have been identified as reflecting strong-positive selection in human
populations, connections between candidate loci and specific selective pressures often …

Disentangling signatures of selection before and after European colonization in Latin Americans

J Mendoza-Revilla, JC Chacón-Duque… - Molecular biology …, 2022 - academic.oup.com
Throughout human evolutionary history, large-scale migrations have led to intermixing (ie,
admixture) between previously separated human groups. Although classical and recent …