Combating antimicrobial resistance in malaria, HIV and tuberculosis

M Duffey, RW Shafer, J Timm, JN Burrows… - Nature Reviews Drug …, 2024 - nature.com
Antimicrobial resistance poses a significant threat to the sustainability of effective treatments
against the three most prevalent infectious diseases: malaria, human immunodeficiency …

[HTML][HTML] Outwitting evolution: fighting drug-resistant TB, malaria, and HIV

DE Goldberg, RF Siliciano, WR Jacobs - Cell, 2012 - cell.com
Although caused by vastly different pathogens, the world's three most serious infectious
diseases, tuberculosis, malaria, and HIV-1 infection, share the common problem of drug …

Resisting resistance: is there a solution for malaria?

BK Verlinden, A Louw, LM Birkholtz - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Currently, widely used antimalarial drugs have a limited clinical lifespan due to
parasite resistance development. With resistance continuously rising, antimalarial drug …

Emerging themes in drug resistance

G Arora, A Kulshreshtha, K Arora, P Talwar… - Drug resistance in …, 2017 - Springer
In the last century, advances in biomedical sciences led to improvements in quality of human
life mainly by decreasing the disease burden and providing various healthcare innovations …

Drug‐resistant malaria− an insight

JE Hyde - The FEBS journal, 2007 - Wiley Online Library
Despite intensive research extending back to the 1930s, when the first synthetic antimalarial
drugs made their appearance, the repertoire of clinically licensed formulations remains very …

Mechanisms of drug resistance in malaria: current and new challenges

P Cravo, R Culleton, A Afonso… - Anti-Infective Agents …, 2006 - ingentaconnect.com
Anti-malarial chemotherapy based on a limited number of drugs has been the mainstay of
malaria control for many decades. However, the lack of new effective and affordable drugs …

A comparative review on current and future drug targets against bacteria & malaria

UK Rout, AS Sanket, BS Sisodia… - Current Drug …, 2020 - ingentaconnect.com
Long before the discovery of drugs like 'antibiotic and anti-parasitic drugs', the infectious
diseases caused by pathogenic bacteria and parasites remain as one of the major causes of …

Molecular mechanism of drug resistance: common themes

CMS Kumar - Drug Resistance in Bacteria, Fungi, Malaria, and …, 2017 - Springer
Antibiotics are the chemical or biochemical moieties that specifically and effectively inhibit
the growth of a pathogen but not the host organism and thus are employed in the treatment …

Mechanisms of Antimicrobial Resistance: Highlights on Current Advance Methods for Detection of Drug Resistance and Current Pipeline Antitubercular Agents

S Prasad, S VP, HS Abbas… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Background: Sir Alexander Fleming accidentally discovered antibiotics in 1928. Antibiotics
have played a significant role in treating infectious diseases. The extensive use of antibiotics …

[HTML][HTML] Mechanisms and Action of Drug Resistance on Mycobacterium tuberculosis

U Brammachary, V Ramachandra, S Palavesam… - 2022 - intechopen.com
Tuberculosis (TB) remains the most challenging infection to treat worldwide. The
contemporary TB regimens consist of 6–9 months of daily doses of four drugs in the existing …