Diabetic kidney disease (DKD) is a prevalent and severe complications of diabetes and
serves as the primary cause of end-stage kidney disease (ESKD) globally. Increasing …

Diabetic nephropathy (DN), a prevalent complication of diabetes mellitus (DM), is clinically
marked by progressive proteinuria and a decline in glomerular filtration rate. The etiology …

Diabetes mellitus is an increasingly prevalent disease around the globe. The epidemic of
diabetes mellitus and its complications pretenses the foremost health threat globally …

Background: Diabetic nephropathy (DN) is one of the most serious complications of diabetes
mellitus and the main cause of the end-stage renal disease (ESRD). Activation of the NLRP3 …

Abstract Background The Nucleotide binding and oligomerization domain-like
receptorfamily pyrin domain-containing 3 (NLRP3)-inflammasome plays an important role in …

Highlights•NLRP3 inflammasome activity plays an important role in inflammatory
responses.•NLRP3 inflammasome is also implicated in diabetic nephropathy (DN) …

Systemic lupus erythematosus (SLE) is a multisystem autoimmune inflammatory condition
that affects multiple organs and provokes extensive and severe clinical manifestations …

Diabetic nephropathy (DN) is one of the most common complications of diabetes and the
main cause of end-stage renal disease (ESRD). The inflammatory response plays a key role …

Diabetes, a common metabolic disease with various complications, is becoming a serious
global health pandemic. So far there are many approaches in the management of diabetes; …

Abstract Background Toll-like receptors (TLRs) are critical sensors for the conservation of
bacterial molecules and play a key role in host defense against pathogens. The effect of …