This article provides an overview of neuroimaging biomarkers in experimental
epileptogenesis and refractory epilepsy. Neuroimaging represents a gold standard and …

Human neuroimaging has had a major impact on the biological understanding of epilepsy
and the relationship between pathophysiology, seizure management, and outcomes. This …

Abstract Information about epileptogenesis-associated changes in protein expression
patterns is of particular interest for future selection of target and biomarker candidates …

Despite intense research efforts, the knowledge about the mechanisms of epileptogenesis
and epilepsy is still considered incomplete and limited. However, an in-depth understanding …

Epileptogenesis, a process leading to a reduced threshold for seizures after transient brain
insults, as well as the mechanisms underlying the propensity to generate spontaneous …

Epilepsy is a common neurological disorder, which is not well understood at the molecular
level. Exactly why some brain regions produce epileptic discharges and others do not is not …

The heterogeneity of epilepsy syndromes and pathologies creates a great challenge for the
search for biomarkers. Not surprisingly, identification of a marker that is specific and …

Epilepsy can be a devastating disorder. In addition to debilitating seizures, epilepsy can
cause cognitive and emotional problems with reduced quality of life. Therefore, the major …

Much progress has been made in the field studying the process of epileptogenesis via
neuroimaging techniques. Conventional imaging methods include magnetic resonance …

Epileptogenesis refers to a process in which an initial brain-damaging insult triggers a
cascade of molecular and cellular changes that eventually lead to the occurrence of …