Abstract α-Synuclein (α-Syn) has been extensively studied for its structural and biophysical
properties owing to its pathophysiological role in Parkinson's disease (PD). Lewy bodies …

The aggregation of the protein alpha-synuclein (α-SYN) is believed to be a critical event in
Parkinson's disease (PD). α-SYN is characterized by a remarkable conformational plasticity …

α-Synuclein (α-Syn) aggregation is directly linked with Parkinson's disease (PD)
pathogenesis. Here, we analyzed the aggregation of newly discovered α-Syn missense …

Cytoplasmic deposition of aberrantly misfolded α-synuclein (α-Syn) is a common feature of
synucleinopathies, including Parkinson's disease (PD). However, the precise pathogenic …

Alpha-synuclein (α-syn) is a small protein that, in neurons, localizes predominantly to
presynaptic terminals. Due to elevated conformational plasticity, which can be affected by …

α-Synuclein (αsyn) is an abundant brain neuronal protein that can misfold and polymerize to
form toxic fibrils coalescing into pathologic inclusions in neurodegenerative diseases …

Disorders characterized by α-synuclein (α-syn) accumulation, Lewy body formation and
parkinsonism (and in some cases dementia) are collectively known as Lewy body diseases …

α-Synuclein (α-syn) is an intrinsically disordered protein abundantly distributed in
presynaptic terminals. Aggregation of α-syn into Lewy bodies (LB) is a molecular hallmark of …

α-Synuclein (α-syn), a small highly conserved presynaptic protein containing 140 amino
acids, is thought to be the main pathological hallmark in related neurodegenerative …

α-synuclein (α-syn) is a synaptic protein in which four mutations (A53T, A30P, E46K and
gene triplication) have been found to cause an autosomal dominant form of Parkinson's …