[图书][B] The isolation, culture-expansion, cryopreservation, characterization, and properties of umbilical cord-derived mesenchymal stromal cells and their extracellular …

AB Wright - 2021 - search.proquest.com
Mesenchymal stromal cells (MSCs) are of therapeutic interest due to their
immunomodulatory and regenerative properties. As a therapeutic, MSCs have limitations …

Isolation and characterization of extracellular vesicles derived from human umbilical cord mesenchymal stem cells

N Ridzuan, D Widera, BH Yahaya - Stem Cell Assays: Methods and …, 2022 - Springer
The safety and efficacy of mesenchymal stem cells/marrow stromal cells (MSC) have been
widely studied. Since they are hypoimmunogenic, MSC can escape immune recognition …

The Characteristics and Function of Small Extracellular Vesicles Derived from Human Bone Marrow and Umbilical Cord Mesenchymal Stromal Cells Are Influenced by …

MC Naskou, A Cochran, N Darzenta… - Stem Cells and …, 2024 - liebertpub.com
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSC-EVs) have been
proposed as a novel therapeutic tool with numerous clinically related advantages. However …

Human umbilical cord mesenchymal stem cell‐derived extracellular vesicles: A novel therapeutic paradigm

H Abbaszadeh, F Ghorbani… - Journal of cellular …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been revealed to hold great potential for the
development of new treatment approaches for various diseases. However, the clinical use of …

Product characterization and preclinical evaluation of the biodistribution and safety of umbilical cord mesenchymal stromal cell-derived extracellular vesicles

ZSM Costa-Ferro, GV Rocha, KN da Silva, BD Paredes… - 2023 - researchsquare.com
Background Extracellular vesicles (EVs) represent a new axis of intercellular communication
that can be explored for therapeutic purposes; they have garnered considerable attention for …

[HTML][HTML] Manufacturing and characterization of extracellular vesicles from umbilical cord–derived mesenchymal stromal cells for clinical testing

E Rohde, K Pachler, M Gimona - Cytotherapy, 2019 - Elsevier
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) may deliver
therapeutic effects that are comparable to their parental cells. MSC-EVs are promising …

From mesenchymal stromal cells to engineered extracellular vesicles: a new therapeutic paradigm

J Johnson, M Shojaee, J Mitchell Crow… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells obtained from many tissues
including bone marrow, adipose tissue, umbilical cord, amniotic fluid, and placenta. MSCs …

[HTML][HTML] Comparison of umbilical cord tissue-derived mesenchymal stromal cells isolated from cryopreserved material and extracted by explantation and digestion …

ML Skiles, AJ Marzan, KS Brown, JM Shamonki - Cytotherapy, 2020 - Elsevier
Background aims Umbilical cord (UC) tissue is recognized as an advantageous source of
mesenchymal stromal cells (MSCs), whose therapeutic properties are being actively …

Efficient expansion of mesenchymal stromal cells from umbilical cord under low serum conditions

J Girdlestone, VA Limbani, AJ Cutler, CV Navarrete - 2009 - Taylor & Francis
Background Mesenchymal stromal cells (MSC) are of clinical interest for their potential use
in regenerative medicine and immunotherapy. Originally derived from bone marrow (BM) …

[HTML][HTML] Umbilical cord mesenchymal stromal cell-derived extracellular vesicles lack the potency to immunomodulate human monocyte-derived macrophages in vitro

TB da Silva, E Rendra, CAW David, K Bieback… - Biomedicine & …, 2023 - Elsevier
Mesenchymal stromal cells (MSCs) have been reported to display efficacy in a variety of
preclinical models, but without long-term engraftment, suggesting a role for secreted factors …