Atypical brain connectivity is a major contributor to the pathophysiology of
neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 …

The precise development of the neocortex is a prerequisite for higher cognitive and
associative functions. Despite numerous advances that have been made in understanding …

Thousand and one amino‐acid kinase 1 (TAOK1) is a MAP3K protein kinase, regulating
different mitogen‐activated protein kinase pathways, thereby modulating a multitude of …

How neurons develop their morphology is an important question in neurobiology. Here we
describe a new pathway that specifically affects the formation of basal dendrites and axonal …

Genetic studies of autism spectrum disorder (ASD) have revealed multigene variations that
converge on synaptic dysfunction. DOCK4, a gene at 7q31. 1 that encodes the Rac1 …

Autism spectrum disorder (ASD) and Alzheimer's disease (AD) are two different neurological
disorders that share common clinical features, such as language impairment, executive …

Abnormalities in dendritic spines are manifestations of several neurodevelopmental and
psychiatric diseases. TAOK2 is one of the genes in the 16p11. 2 locus, copy number …

Although twin studies indicate clear genetic bases of autism spectrum disorder (ASD), the
precise mechanisms through which genetic variations causally result in ASD are poorly …

De novo variants represent a significant cause of neurodevelopmental delay and intellectual
disability. A genetic basis can be identified in only half of individuals who have …

The Wnt/β-catenin pathway contains multiple high-confidence risk genes that are linked to
neurodevelopmental disorders, including autism spectrum disorder. However, its ubiquitous …