Rapid identification of early renal damage in asymptomatic hyperuricemia patients based on urine Raman spectroscopy and bioinformatics analysis

X Kong, H Liang, W An, S Bai, Y Miao, J Qiang… - Frontiers in …, 2023 - frontiersin.org
Objective: The issue of when to start treatment in patients with hyperuricemia (HUA) without
gout and chronic kidney disease (CKD) is both important and controversial. In this study …

Raman Spectral Characterization of Urine for Rapid Diagnosis of Acute Kidney Injury

MJ Jeng, M Sharma, CC Lee, YS Lu, CL Tsai… - Journal of Clinical …, 2022 - mdpi.com
Acute kidney injury (AKI) is a common syndrome characterized by various etiologies and
pathophysiologic processes that deteriorate kidney function. The aim of this study is to …

Surface-enhanced Raman Spectroscopy in urinalysis of hypertension patients with kidney disease

AC Espinosa-Garavito, EN Quiroz, NJ Galán-Freyle… - Scientific Reports, 2024 - nature.com
Arterial hypertension (AH) is a multifactorial and asymptomatic disease that affects vital
organs such as the kidneys and heart. Considering its prevalence and the associated …

Reliable quantitative detection of uric acid in urine by surface-enhanced Raman spectroscopy with endogenous internal standard

JW Zhou, XB Zheng, HS Liu, BY Wen, YC Kou… - Biosensors and …, 2024 - Elsevier
Abnormal levels of uric acid (UA) in urine serve as warning signs for gout and metabolic
cardiovascular diseases, necessitating the monitoring of UA levels for early prevention …

Analysis of urine Raman spectra differences from patients with diabetes mellitus and renal pathologies

V Kavuru, RS Senger, JL Robertson, D Choudhury - PeerJ, 2023 - peerj.com
Background Chronic kidney disease (CKD) poses a major public health burden. Diabetes
mellitus (DM) is one of the major causes of CKD. In patients with DM, it can be difficult to …

Correlating the amount of urea, creatinine, and glucose in urine from patients with diabetes mellitus and hypertension with the risk of developing renal lesions by …

JAM Bispo, EE de Sousa Vieira… - … of biomedical optics, 2013 - spiedigitallibrary.org
Patients with diabetes mellitus and hypertension (HT) diseases are predisposed to kidney
diseases. The objective of this study was to identify potential biomarkers in the urine of …

Biochemical analysis of urine samples from diabetic and hypertensive patients without renal dysfunction using spectrophotometry and raman spectroscopy techniques …

EE de Sousa Vieira, L Silveira Jr, HC Carvalho… - Bioengineering, 2022 - mdpi.com
The purpose of this study was to perform a comparative biochemical analysis between
conventional spectrophotometry and Raman spectroscopy, techniques used for diagnoses …

Urine Raman spectroscopy for rapid and inexpensive diagnosis of chronic renal failure (CRF) using multiple classification algorithms

C Chen, L Yang, J Zhao, Y Yuan, C Chen, J Tang… - Optik, 2020 - Elsevier
Chronic renal failure (CRF) is a symptom that is caused by kidney damage that deteriorates
to the end stage. If not treated in time, CRF will worse into uraemia, which greatly reduces …

Quantifying creatinine and urea in human urine through Raman spectroscopy aiming at diagnosis of kidney disease

CJ Saatkamp, ML de Almeida… - … of biomedical optics, 2016 - spiedigitallibrary.org
Due to their importance in the regulation of metabolites, the kidneys need continuous
monitoring to check for correct functioning, mainly by urea and creatinine urinalysis. This …

The biomarkers discovery of hyperuricemia and gout: proteomics and metabolomics

X Wu, C You - PeerJ, 2023 - peerj.com
Background Hyperuricemia and gout are a group of disorders of purine metabolism. In
recent years, the incidence of hyperuricemia and gout has been increasing, which is a …