Ionizing radiation (IR) has found widespread application in modern medicine, including
medical imaging and radiotherapy. As a result, both patients and healthcare professionals …

It is estimated that more than half of cancer patients undergo radiotherapy during the course
of their treatment. Despite its beneficial therapeutic effects on tumor cells, exposure to high …

During radiotherapy, ionizing irradiation interacts with biological systems to produce free
radicals, which attacks various cellular components. The hematopoietic system is well …

Antioxidants are part of the primary cellular defense against radiation-generated free
radicals. Reports on low-level chronic administration of melatonin with its antiradiation …

While radiation hazards, due to free radical generation, present an enormous challenge for
biological and medical safety, melatonin is a potent scavenger of a variety of free radicals …

Radiotherapy has a key role in cancer treatment in more than half of patients with cancer.
The management of severe side effects of this treatment modality is a limiting factor to …

In spite of the fact that radiotherapy is a common and effective tool for cancer treatment; the
radio sensitivity of normal tissues adjacent to the tumor which are unavoidably exposed to …

Ionizing radiation is classified as a potent carcinogen, and its injury to living cells is, to a
large extent, due to oxidative stress. The molecule most often reported to be damaged by …

Cancer remains among the most challenging human diseases. Several lines of evidence
suggest that carcinogenesis is a complex process that is initiated by DNA damage …

This study was designed to study the effects of the potential radioprotective properties of
pharmacological doses of melatonin against organ damage induced by whole-body …