Interleukin-8 (IL-8, CXCL8) is a pro-inflammatory chemokine produced by various cell types
to recruit leukocytes to sites of infection or tissue injury. Acquisition of IL-8 and/or its …

In humans, Interleukin-8 (IL-8 or CXCL8) is a granulocytic chemokine with multiple roles
within the tumor microenvironment (TME), such as recruiting immunosuppressive cells to the …

The tumor microenvironment represents a dynamic and complex cellular network involving
intricate communications between the tumor and highly heterogeneous groups of cells …

Abstract Interleukin-8 (CXCL8) produced in the tumor microenvironment correlates with poor
response to checkpoint inhibitors and is known to chemoattract and activate …

Abstract Interleukin-8 (IL-8) is a proinflammatory CXC chemokine associated with the
promotion of neutrophil chemotaxis and degranulation. This chemokine activates multiple …

Tumor progression relies on the ability of cancer cells to effectively invade surrounding
tissues and propagate. Among the many mechanisms that contribute to tumor progression is …

A long-standing question in the field of tumor immunotherapy is how Th2 cytokines block
tumor growth. Their antitumor effects are particularly prominent when they are secreted …

Abstract Interleukin-2 (IL-2) and its receptor (IL-2R) are essential in orchestrating immune
responses. Their function and expression in the tumor microenvironment make them …

The tumor microenvironment comprises stromal and tumor cells which interact with each
other through complex cross-talks that are mediated by a variety of growth factors, cytokines …

Abstract Interleukin-8 (CXCL8) was originally described as a chemokine whose main
function is the attraction of a polymorphonuclear inflammatory leukocyte infiltrate acting on …