Understanding the developmental origins of health and disease is integral to overcome the
global tide of obesity and its metabolic consequences, including atherosclerotic …

While adult lifestyle factors undoubtedly contribute to the incidence of obesity and its
attendant disorders, mounting evidence suggests that programming of obesity may occur …

Evolutionary and developmental perspectives add considerably to our understanding of the
aetiology of obesity and its related disorders. One pathway to obesity represents the …

Converging lines of evidence from epidemiological studies and animal models now indicate
that the origins of obesity and related metabolic disorders lie not only in the interaction …

Although variation in individual lifestyle and genotype are important factors in explaining
individual variation in the risk of developing obesity in an obesogenic environment, there is …

The metabolic syndrome epidemic, including a marked increase in the prevalence of obesity
and gestational diabetes mellitus (GDM) among pregnant women, represents a significant …

Extensive human and animal model data show that nutrition and other environmental
influences during critical periods of embryonic, fetal, and early postnatal life can affect the …

It is now well accepted that early life events can contribute substantially to the likelihood of
an individual becoming obese, although many of the mechanisms for this are not well …

Maternal obesity can profoundly affect offspring phenotype and predisposition to obesity and
metabolic disease. Carefully controlled studies in precocial and altricial mammalian species …

More than 60% of adults in the US are classified as overweight, with most developing
associated metabolic problems. It is increasingly clear that the origins of obesity and …