Histone 4 lysine 5/12 acetylation enables developmental plasticity of Pristionchus mouth form

MS Werner, T Loschko, T King, S Reich… - nature …, 2023 - nature.com
Abstract Development can be altered to match phenotypes with the environment, and the
genetic mechanisms that direct such alternative phenotypes are beginning to be elucidated …

Chromatin remodelling and antisense-mediated up-regulation of the developmental switch gene eud-1 control predatory feeding plasticity

V Serobyan, H Xiao, S Namdeo… - Nature …, 2016 - nature.com
Phenotypic plasticity has been suggested to act through developmental switches, but little is
known about associated molecular mechanisms. In the nematode Pristionchus pacificus, the …

A histone demethylase links the loss of plasticity to nongenetic inheritance and morphological change

NA Levis, EJ Ragsdale - Nature Communications, 2023 - nature.com
Plasticity is a widespread feature of development, enabling phenotypic change based on the
environment. Although the evolutionary loss of plasticity has been linked both theoretically …

[HTML][HTML] A developmental switch coupled to the evolution of plasticity acts through a sulfatase

EJ Ragsdale, MR Müller, C Rödelsperger, RJ Sommer - Cell, 2013 - cell.com
Developmental plasticity has been suggested to facilitate phenotypic diversity, but the
molecular mechanisms underlying this relationship are little understood. We analyzed a …

Conserved nuclear hormone receptors controlling a novel plastic trait target fast-evolving genes expressed in a single cell

B Sieriebriennikov, S Sun, JW Lightfoot, H Witte… - PLoS …, 2020 - journals.plos.org
Environment shapes development through a phenomenon called developmental plasticity.
Deciphering its genetic basis has potential to shed light on the origin of novel traits and …

[HTML][HTML] Environmental influence on Pristionchus pacificus mouth form through different culture methods

MS Werner, B Sieriebriennikov, T Loschko… - Scientific Reports, 2017 - nature.com
Environmental cues can impact development to elicit distinct phenotypes in the adult. The
consequences of phenotypic plasticity can have profound effects on morphology, life cycle …

A sulfotransferase dosage-dependently regulates mouthpart polyphenism in the nematode Pristionchus pacificus

LT Bui, NA Ivers, EJ Ragsdale - Nature communications, 2018 - nature.com
Polyphenism, the extreme form of developmental plasticity, is the ability of a genotype to
produce discrete morphologies matched to alternative environments. Because polyphenism …

The nuclear hormone receptor NHR-40 acts downstream of the sulfatase EUD-1 as part of a developmental plasticity switch in Pristionchus

MR Kieninger, NA Ivers, C Roedelsperger, GV Markov… - Current Biology, 2016 - cell.com
Developmental plasticity, the ability of one genotype to produce distinct phenotypes in
different environments, has been suggested to facilitate phenotypic diversification, and …

Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis

JM Gahan, IU Kouzel, KO Jansen, P Burkhardt… - Nature …, 2022 - nature.com
Chromatin regulation is a key process in development but its contribution to the evolution of
animals is largely unexplored. Chromatin is regulated by a diverse set of proteins, which …

Histone deacetylase-4 is required during early cranial neural crest development for generation of the zebrafish palatal skeleton

A DeLaurier, Y Nakamura, I Braasch, V Khanna… - BMC developmental …, 2012 - Springer
Abstract Background Histone deacetylase-4 (Hdac4) is a class II histone deacetylase that
inhibits the activity of transcription factors. In humans, HDAC4 deficiency is associated with …