Background Because of the debate about whether second-generation antipsychotic drugs
are better than first-generation antipsychotic drugs, we did a meta-analysis of randomised …

The initial enthusiasm about the second-generation or atypical antipsychotic drugs soon
changed into criticism and debate, culminating in the controversial CATIE (Clinical …

Objective: Whether there are differences in efficacy among second-generation
antipsychotics in the treatment of schizophrenia is a matter of heated debate. The authors …

We conducted a systematic review and meta-analysis of randomized controlled trials that
compared second-generation antipsychotic (SGA) drugs with placebo in schizophrenic …

Background Whether or not second-generation antipsychotics (SGAs) represent an
advantage over first-generation antipsychotics (FGAs) in the treatment of schizophrenia is …

Background: Debate continues about the comparative benefits and harms of first-generation
antipsychotics (FGAs) and second-generation antipsychotics (SGAs) in treating …

Background The question of which antipsychotic drug should be preferred for the treatment
of schizophrenia is controversial, and conventional pairwise meta-analyses cannot provide …

Background Second-generation antipsychotic drugs were introduced over a decade ago for
the treatment of schizophrenia; however, their purported clinical effectiveness compared …

Background Systematic reviews based on efficacy trials are inconclusive about which
second generation antipsychotic drug (SGA) should be preferred in normal clinical practice …

Background Consensus panel recommendations regarding choice of an antipsychotic agent
for schizophrenia differ markedly, but most consider second-generation antipsychotics …