[HTML][HTML] The clinical practice of risk reduction for Alzheimer's disease: a precision medicine approach

RS Isaacson, CA Ganzer, H Hristov, K Hackett… - Alzheimer's & …, 2018 - Elsevier
Like virtually all age-related chronic diseases, late-onset Alzheimer's disease (AD) develops
over an extended preclinical period and is associated with modifiable lifestyle and …

Prevention of Alzheimer's disease: lessons learned and applied

JE Galvin - Journal of the American Geriatrics Society, 2017 - Wiley Online Library
Alzheimer's disease (AD) affects more than 5 million Americans, with substantial
consequences for individuals with AD, families, and society in terms of morbidity, mortality …

Dementia prevention in clinical practice

K Niotis, K Akiyoshi, C Carlton… - Seminars in …, 2022 - thieme-connect.com
Over 55 million people globally are living with dementia and, by 2050, this number is
projected to increase to 131 million. This poses immeasurable challenges for patients and …

Precision prevention of Alzheimer's and other dementias: anticipating future needs in the control of risk factors and implementation of disease‐modifying therapies

GB Frisoni, JL Molinuevo, D Altomare… - Alzheimer's & …, 2020 - Wiley Online Library
Empirical evidence suggests that a fair proportion of dementia cases are preventable, that
some preventive actions can be taken immediately, and others may soon be implemented …

[HTML][HTML] Individualized clinical management of patients at risk for Alzheimer's dementia

RS Isaacson, H Hristov, N Saif, K Hackett… - Alzheimer's & …, 2019 - Elsevier
Abstract Introduction Multidomain intervention for Alzheimer's disease (AD) risk reduction is
an emerging therapeutic paradigm. Methods Patients were prescribed individually tailored …

[HTML][HTML] Bridging the translation gap: from dementia risk assessment to advice on risk reduction

KJ Anstey, R Eramudugolla, DE Hosking… - The journal of …, 2015 - ncbi.nlm.nih.gov
Dementia risk reduction is a global health and fiscal priority given the current lack of effective
treatments and the projected increased number of dementia cases due to population …

[HTML][HTML] Paths to Alzheimer's disease prevention: from modifiable risk factors to biomarker enrichment strategies

S Lista, B Dubois, H Hampel - The Journal of nutrition, health and aging, 2015 - Elsevier
Alzheimer's disease (AD) represents an increasing worldwide healthcare epidemic.
Secondary preventive disease-modifying treatments under clinical development are …

[HTML][HTML] Advances in the prevention of Alzheimer's Disease

S Sindi, F Mangialasche, M Kivipelto - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Abstract Alzheimer's disease (AD), the leading cause of dementia, has reached epidemic
proportions, with major social, medical and economical burdens. With no currently available …

Precision medicine for Alzheimer's disease prevention

CL Berkowitz, L Mosconi, O Scheyer… - The Road from …, 2020 - taylorfrancis.com
The role that genetics plays in the development of late-onset Alzheimer's disease (AD) has
been widely studied, with one study estimating genetics to account for more than 50% of the …

[PDF][PDF] Dementia (including Alzheimer's disease) can be prevented: statement supported by international experts

K Yaffe, P Aisen, M Albert, K Anstey - J Alzheimers Dis, 2014 - researchgate.net
• We propose that a concerted effort be made to discover modifiable risk factors for dementia
and to exploit those already identified.• International collaboration is needed on largescale …