Epistasis between genes is traditionally studied with mutations that eliminate protein activity,
but most natural genetic variation is in cis-regulatory DNA and influences gene expression …

Cis-regulatory mutations underlie important crop domestication and improvement traits,.
However, limited allelic diversity has hindered functional dissection of the large number of …

Numerous studies are investigating the basis of complex traits in a wide range of species.
However, largely absent are efforts aimed at examining the possible contribution of natural …

To explore natural biodiversity we developed and examined introgression lines (ILs)
containing chromosome segments of wild species (Solanum pennellii) in the background of …

To understand evolutionary factors that maintain complex trait variation, we sequenced
genomes from a single population of the plant Mimulus guttatus, identifying hundreds of …

The genomes of individuals from the same species vary in sequence as a result of different
evolutionary processes. To examine the patterns of, and the forces shaping, sequence …

Uncovering the genes, variants, and interactions underlying crop diversity is a frontier in
plant genetics. Phenotypic variation often does not reflect the cumulative effect of individual …

Edible fruits, such as that of the tomato plant and other vegetable crops, are markedly
diverse in shape and size. SUN, one of the major genes controlling the elongated fruit shape …

Quantifying the impact of heritable epigenetic variation on complex traits is an emerging
challenge in population genetics. Here, we analyze a population of isogenic Arabidopsis …

Developmental differences between species commonly result from changes in the tissue-
specific expression of genes. Clustering algorithms are a powerful means to detect …