Introduction Current approved COVID-19 vaccines, notably mRNA and adenoviral vectored
technologies, still fail to fully protect against infection and transmission of various SARS-CoV …

Background: Mucosal immunity, including secretory IgA (sIgA), plays an important role in
early defenses against respiratory pathogens. Salivary testing, the most convenient way to …

Background Relevant aspects regarding the SARS-CoV-2 pathogenesis and the systemic
immune response to this infection have been reported. However, the mucosal immune …

Mucosal immune responses are critical to prevent respiratory infections but it is unclear to
what extent antigen specific mucosal secretory IgA (SIgA) antibodies are induced by mRNA …

Although SARS-CoV-2 infects the upper respiratory tract, we know little about the amount,
type, and kinetics of antibodies (Ab) generated in the oral cavity in response to COVID-19 …

ABSTRACT Coronavirus disease 2019 (COVID-19) vaccines have saved millions of lives.
However, variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have …

Immune responses at the respiratory mucosal interface are critical to prevent respiratory
infections but it is unclear to what extent antigen specific mucosal secretory IgA (SIgA) …

In early 2020, a global emergency was upon us in the form of the coronavirus disease 2019
(COVID‐19) pandemic. While horrific in its health, social and economic devastation, one …

SARS-CoV-2 is primarily an airborne infection of the upper respiratory tract, which on
reaching the lungs causes the severe acute respiratory disease, COVID-19. Its first contact …

While IgM and IgG response to SARS-CoV-2 has been extensively studied, relatively little is
known about secretory IgA (sIgA) response in respiratory mucosa. Here we report IgA …