Aging is a major risk factor for numerous chronic diseases. Vaccination offers a promising
strategy to combat these age-related diseases by targeting specific antigens and inducing …

Aging-related decline in immune functions, termed immunosenescence, is a primary cause
of reduced protective responses to vaccines in the elderly, due to impaired induction of …

The development of senomorphic drugs to attenuate the senescent phenotype and
senolytics to clear pro-inflammatory senescent cells (SCs) to treat aging-associated …

As the world's population grows older, vaccination is becoming a key strategy for promoting
healthy aging. Despite scientific progress in adult vaccine development, obstacles such as …

Immunosenescence increases the risk and severity of diseases in elderly individuals and
leads to impaired vaccine-induced immunity. With aging of the global population and the …

Human aging is reaching epidemic proportions as life expectancy increases and birth rate
decreases. These demographic trends have led to a sharp increase in the diseases of …

Alzheimer disease is a devastating chronic disease without adequate therapy. More than 10
years ago, it was demonstrated in transgenic mouse models that vaccination may be a …

The demographics of the world's population are changing, with many adults now surviving
into their 80s. With this change comes the need to protect the aging and other underserved …

Vaccination is the most effective measure to protect against infections. However, with
increasing age, there is a progressive decline in the ability of the immune system to both …

Vaccines are powerful public health tools that have been of tremendous benefit in protecting
vulnerable populations worldwide from many pathogens. However, vaccine-preventable …