From bulk, single-cell to spatial RNA sequencing

X Li, CY Wang - International journal of oral science, 2021 - nature.com
RNA sequencing (RNAseq) can reveal gene fusions, splicing variants, mutations/indels in
addition to differential gene expression, thus providing a more complete genetic picture than …

Changing technologies of RNA sequencing and their applications in clinical oncology

Y Wang, M Mashock, Z Tong, X Mu, H Chen… - Frontiers in …, 2020 - frontiersin.org
RNA sequencing (RNAseq) is one of the most commonly used techniques in life sciences,
and has been widely used in cancer research, drug development, and cancer diagnosis and …

RNA sequencing: new technologies and applications in cancer research

M Hong, S Tao, L Zhang, LT Diao, X Huang… - Journal of hematology & …, 2020 - Springer
Over the past few decades, RNA sequencing has significantly progressed, becoming a
paramount approach for transcriptome profiling. The revolution from bulk RNA sequencing …

What are the applications of single-cell RNA sequencing in cancer research: a systematic review

L Li, F Xiong, Y Wang, S Zhang, Z Gong, X Li… - Journal of Experimental …, 2021 - Springer
Single-cell RNA sequencing (scRNA-seq) is a tool for studying gene expression at the
single-cell level that has been widely used due to its unprecedented high resolution. In the …

High throughput single cell RNA sequencing, bioinformatics analysis and applications

X Huang, S Liu, L Wu, M Jiang, Y Hou - Single cell biomedicine, 2018 - Springer
Single cell sequencing (SCS) can be harnessed to acquire the genomes, transcriptomes
and epigenomes from individual cells. Next generation sequencing (NGS) technology is the …

Advances in single-cell RNA sequencing and its applications in cancer research

D Huang, N Ma, X Li, Y Gou, Y Duan, B Liu… - Journal of hematology & …, 2023 - Springer
Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

Single‐cell RNA sequencing in cancer research

Y Zhang, D Wang, M Peng, L Tang, J Ouyang… - Journal of Experimental …, 2021 - Springer
Single-cell RNA sequencing (scRNA-seq), a technology that analyzes transcriptomes of
complex tissues at single-cell levels, can identify differential gene expression and epigenetic …

The evolution of single-cell RNA sequencing technology and application: progress and perspectives

S Wang, ST Sun, XY Zhang, HR Ding, Y Yuan… - International Journal of …, 2023 - mdpi.com
As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has
become a powerful tool for describing cell subpopulation classification and cell …

[HTML][HTML] Advances in single-cell RNA sequencing and its applications in cancer research

S Zhu, T Qing, Y Zheng, L Jin, L Shi - Oncotarget, 2017 - ncbi.nlm.nih.gov
Unlike population-level approaches, single-cell RNA sequencing enables transcriptomic
analysis of an individual cell. Through the combination of high-throughput sequencing and …

Granatum: a graphical single-cell RNA-Seq analysis pipeline for genomics scientists

X Zhu, TK Wolfgruber, A Tasato, C Arisdakessian… - Genome medicine, 2017 - Springer
Background Single-cell RNA sequencing (scRNA-Seq) is an increasingly popular platform
to study heterogeneity at the single-cell level. Computational methods to process scRNA …