A randomized clinical trial of combination chemotherapy with and without low‐molecular‐weight heparin in small cell lung cancer
M Altinbas, HS Coskun, O Er, M Ozkan… - … of thrombosis and …, 2004 - Wiley Online Library
Background Small cell lung cancer (SCLC) is a chemotherapy‐responsive tumor type but
most patients ultimately experience disease progression. SCLC is associated with …
most patients ultimately experience disease progression. SCLC is associated with …
Subcutaneous heparin treatment increases survival in small cell lung cancer
B Lebeau, C Chastang, JM Brechot, F Capron… - Cancer, 1994 - Wiley Online Library
Background. A positive influence of anticoagulant treatment in small cell lung cancer (SCLC)
has been sug gested by experimental and clinical data. Methods. In a multicenter clinical …
has been sug gested by experimental and clinical data. Methods. In a multicenter clinical …
Randomized phase III trial of standard therapy plus low molecular weight heparin in patients with lung cancer: FRAGMATIC trial
F Macbeth, S Noble, J Evans, S Ahmed… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Venous thromboembolism (VTE) is common in cancer patients. Evidence has
suggested that low molecular weight heparin (LMWH) might improve survival in patients with …
suggested that low molecular weight heparin (LMWH) might improve survival in patients with …
A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the Cancer and Leukemia Group B.
AP Chahinian, KJ Propert, JH Ware… - Journal of Clinical …, 1989 - ascopubs.org
The Cancer and Leukemia Group B (CALGB) conducted a prospective randomized trial to
evaluate the role of warfarin and alternating chemotherapy in extensive small-cell lung …
evaluate the role of warfarin and alternating chemotherapy in extensive small-cell lung …
[HTML][HTML] The effect of low molecular weight heparin on survival in cancer patients: an updated systematic review and meta‐analysis of randomized trials
D Sanford, A Naidu, N Alizadeh… - Journal of Thrombosis and …, 2014 - Elsevier
Background Tumors may exploit the coagulation system to enhance the survival and
dissemination of cancer cells. Some studies have suggested that heparin and low molecular …
dissemination of cancer cells. Some studies have suggested that heparin and low molecular …
Randomized trial of chemotherapy and radiation therapy with or without warfarin for limited-stage small-cell lung cancer: a Cancer and Leukemia Group B study.
LH Maurer, JE Herndon 2nd, DR Hollis… - Journal of clinical …, 1997 - ascopubs.org
PURPOSE Studies by the Veterans Administration Cooperative Studies Program and
Cancer and Leukemia Group B (CALGB) suggested that the addition of warfarin to …
Cancer and Leukemia Group B (CALGB) suggested that the addition of warfarin to …
Anti-angiogenic therapy using thalidomide combined with chemotherapy in small cell lung cancer: a randomized, double-blind, placebo-controlled trial
Background Cancer cells rely on angiogenesis for growth and dissemination, and small cell
lung cancer (SCLC) is a highly angiogenic tumor. We evaluated thalidomide, an anti …
lung cancer (SCLC) is a highly angiogenic tumor. We evaluated thalidomide, an anti …
Hypercoagulability and lung cancer
FCA Marinho, TY Takagaki - Jornal Brasileiro de Pneumologia, 2008 - SciELO Brasil
The relationship between cancer and coagulopathy was suggested by Trousseau nearly
150 years ago. Later, it became more evident that oncologic patients are at a higher risk of …
150 years ago. Later, it became more evident that oncologic patients are at a higher risk of …
Low-molecular-weight heparin and cancer
LR Zacharski, DL Ornstein… - Seminars in thrombosis …, 2000 - thieme-connect.com
Heparin is a familiar anticoagulant drug with properties that may impede tumor growth; it
modifies properties of cells that contribute to malignant dissemination such as angiogenesis …
modifies properties of cells that contribute to malignant dissemination such as angiogenesis …
Randomized comparison of low molecular weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism
AYY Lee, FR Rickles, JA Julian, M Gent… - Journal of Clinical …, 2005 - ascopubs.org
Purpose Experimental studies and indirect clinical evidence suggest that low molecular
weight heparins may have antineoplastic effects. We investigated the influence of a low …
weight heparins may have antineoplastic effects. We investigated the influence of a low …